Dopamine, immunity, and disease
B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - ASPET
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …
regulating many processes including reward, movement, and cognition. Dopamine also …
GM-CSF: A double-edged sword in cancer immunotherapy
A Kumar, A Taghi Khani, A Sanchez Ortiz… - Frontiers in …, 2022 - frontiersin.org
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that drives the
generation of myeloid cell subsets including neutrophils, monocytes, macrophages, and …
generation of myeloid cell subsets including neutrophils, monocytes, macrophages, and …
Macrophages in intestinal homeostasis and inflammatory bowel disease
LM Hegarty, GR Jones, CC Bain - Nature Reviews Gastroenterology & …, 2023 - nature.com
Macrophages are essential for the maintenance of intestinal homeostasis, yet appear to be
drivers of inflammation in the context of inflammatory bowel disease (IBD). How these …
drivers of inflammation in the context of inflammatory bowel disease (IBD). How these …
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor
Functional tissue regeneration is required for the restoration of normal organ homeostasis
after severe injury. Some organs, such as the intestine, harbour active stem cells throughout …
after severe injury. Some organs, such as the intestine, harbour active stem cells throughout …
Guidelines for the use of flow cytometry and cell sorting in immunological studies*
A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2017 - Wiley Online Library
From a technical point of view a flow cytometer is a light detection device capable of
detecting photons of different wavelengths over a high dynamic range. In order to achieve a …
detecting photons of different wavelengths over a high dynamic range. In order to achieve a …
Macrophages in the gut: Masters in multitasking
M Delfini, N Stakenborg, MF Viola, G Boeckxstaens - Immunity, 2022 - cell.com
The gastrointestinal tract has the important task of absorbing nutrients, a complex process
that requires an intact barrier allowing the passage of nutrients but that simultaneously …
that requires an intact barrier allowing the passage of nutrients but that simultaneously …
Origin, differentiation, and function of intestinal macrophages
CC Bain, A Schridde - Frontiers in immunology, 2018 - frontiersin.org
Macrophages are increasingly recognized as essential players in the maintenance of
intestinal homeostasis and as key sentinels of the intestinal immune system. However …
intestinal homeostasis and as key sentinels of the intestinal immune system. However …
[HTML][HTML] Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment
Macrophages are critical for innate immune defense and also control organ homeostasis in
a tissue-specific manner. They provide a fitting model to study the impact of ontogeny and …
a tissue-specific manner. They provide a fitting model to study the impact of ontogeny and …
GM-CSF: from growth factor to central mediator of tissue inflammation
The granulocyte-macrophage colony-stimulating factor (GM-CSF) was initially classified as a
hematopoietic growth factor. However, unlike its close relatives macrophage CSF (M-CSF) …
hematopoietic growth factor. However, unlike its close relatives macrophage CSF (M-CSF) …
T cell responses to the microbiota
II Ivanov, T Tuganbaev, AN Skelly… - Annual review of …, 2022 - annualreviews.org
The immune system employs recognition tools to communicate with its microbial
evolutionary partner. Among all the methods of microbial perception, T cells enable the …
evolutionary partner. Among all the methods of microbial perception, T cells enable the …