Non-coding RNAs and their integrated networks

P Zhang, W Wu, Q Chen, M Chen - Journal of integrative …, 2019 - degruyter.com
Eukaryotic genomes are pervasively transcribed. Besides protein-coding RNAs, there are
different types of non-coding RNAs that modulate complex molecular and cellular …

Emerging role of non‐coding RNA in health and disease

GK Bhatti, N Khullar, IS Sidhu, US Navik… - Metabolic brain …, 2021 - Springer
Human diseases have always been a significant turf of concern since the origin of mankind.
It is cardinal to know the cause, treatment, and cure for every disease condition. With the …

Chondrosarcoma: An overview of clinical behavior, molecular mechanisms mediated drug resistance and potential therapeutic targets

E Nazeri, MG Savadkoohi, K Majidzadeh-A… - Critical reviews in …, 2018 - Elsevier
Sarcomas are known as a heterogeneous class of cancers arisen in the connective tissues
and demonstrated various histological subtypes including both soft tissue and bone origin …

The roles of noncoding RNAs in the development of osteosarcoma stem cells and potential therapeutic targets

J Liu, G Shang - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Osteosarcoma (OS) is the common bone tumor in children and adolescents. Because of
chemotherapy resistance, the OS patients have a poor prognosis. The one reason of …

Circulating serum microRNAs including senescent miR-31-5p are associated with incident fragility fractures in older postmenopausal women with type 2 diabetes …

U Heilmeier, M Hackl, F Schroeder, S Torabi, P Kapoor… - Bone, 2022 - Elsevier
Fragility fractures are an important hallmark of aging and an increasingly recognized
complication of Type 2 diabetes (T2D). T2D individuals have been found to exhibit an …

Emerging roles and potential applications of non-coding RNAs in cervical cancer

D Parashar, A Singh, S Gupta, A Sharma, MK Sharma… - Genes, 2022 - mdpi.com
Cervical cancer (CC) is a preventable disease using proven interventions, specifically
prophylactic vaccination, pervasive disease screening, and treatment, but it is still the most …

Long noncoding RNA SNHG7 promotes the tumor growth and epithelial-to-mesenchymal transition via regulation of miR-34a signals in osteosarcoma

Y Deng, F Zhao, Z Zhang, F Sun… - Cancer Biotherapy & …, 2018 - liebertpub.com
The long noncoding RNA (LncRNA) SNHG7 (small nuclear RNA host gene 7) is a novel
LncRNA and functions as an oncogene to promote tumor proliferation and inhibits apoptosis …

microRNA-216b enhances cisplatin-induced apoptosis in osteosarcoma MG63 and SaOS-2 cells by binding to JMJD2C and regulating the HIF1α/HES1 signaling axis

D Yang, T Xu, L Fan, K Liu, G Li - Journal of Experimental & Clinical …, 2020 - Springer
Background Although cisplatin-based chemotherapy represents the standard regimen for
osteosarcoma (OS), OS patients often exhibit treatment failure and poor prognosis due to …

Advancements in clinical RNA therapeutics: Present developments and prospective outlooks

PE Saw, E Song - Cell Reports Medicine, 2024 - cell.com
RNA molecules have emerged as promising clinical therapeutics due to their ability to
target" undruggable" proteins or molecules with high precision and minimal side effects …

[HTML][HTML] Exploring the Role of Noncoding RNAs in Cancer Diagnosis, Prognosis, and Precision Medicine.

B Eldakhakhny, AM Sutaih, MA Siddiqui… - Non-coding RNA …, 2024 - Elsevier
This review article studies the complex field of noncoding RNAs (ncRNAs) in cancer biology,
focusing on their potential use as biomarkers and therapeutic targets. ncRNAs include …