Cannabis addiction and the brain: a review

A Zehra, J Burns, CK Liu, P Manza, CE Wiers… - Journal of Neuroimmune …, 2018 - Springer
Cannabis is the most commonly used substance of abuse in the United States after alcohol
and tobacco. With a recent increase in the rates of cannabis use disorder (CUD) and a …

Inflammation and the neural diathesis-stress hypothesis of schizophrenia: a reconceptualization

OD Howes, R McCutcheon - Translational psychiatry, 2017 - nature.com
An interaction between external stressors and intrinsic vulnerability is one of the longest
standing pathoaetiological explanations for schizophrenia. However, novel lines of evidence …

[HTML][HTML] Modulation of myelopoiesis progenitors is an integral component of trained immunity

I Mitroulis, K Ruppova, B Wang, LS Chen, M Grzybek… - Cell, 2018 - cell.com
Trained innate immunity fosters a sustained favorable response of myeloid cells to a
secondary challenge, despite their short lifespan in circulation. We thus hypothesized that …

Endocannabinoid signalling and the deteriorating brain

V Di Marzo, N Stella, A Zimmer - Nature Reviews Neuroscience, 2015 - nature.com
Ageing is characterized by the progressive impairment of physiological functions and
increased risk of developing debilitating disorders, including chronic inflammation and …

Cerebellar dopamine D2 receptors regulate social behaviors

L Cutando, E Puighermanal, L Castell, P Tarot… - Nature …, 2022 - nature.com
The cerebellum, a primary brain structure involved in the control of sensorimotor tasks, also
contributes to higher cognitive functions including reward, emotion and social interaction …

The neural substrate of reward anticipation in health: a meta-analysis of fMRI findings in the monetary incentive delay task

RP Wilson, M Colizzi, MG Bossong, P Allen… - Neuropsychology …, 2018 - Springer
The monetary incentive delay task breaks down reward processing into discrete stages for
fMRI analysis. Here we look at anticipation of monetary gain and loss contrasted with neutral …

Infectious immunity in the central nervous system and brain function

RS Klein, C Garber, N Howard - Nature immunology, 2017 - nature.com
Inflammation is emerging as a critical mechanism underlying neurological disorders of
various etiologies, yet its role in altering brain function as a consequence of neuroinfectious …

Microglia in neuroimmunopharmacology and drug addiction

H Li, LR Watkins, X Wang - Molecular Psychiatry, 2024 - nature.com
Drug addiction is a chronic and debilitating disease that is considered a global health
problem. Various cell types in the brain are involved in the progression of drug addiction …

Genome-wide association study implicates CHRNA2 in cannabis use disorder

D Demontis, VM Rajagopal, TE Thorgeirsson… - Nature …, 2019 - nature.com
Cannabis is the most frequently used illicit psychoactive substance worldwide; around one
in ten users become dependent. The risk for cannabis use disorder (CUD) has a strong …

THC and CBD: villain versus hero? Insights into adolescent exposure

N Pintori, F Caria, MA De Luca, C Miliano - International Journal of …, 2023 - mdpi.com
Cannabis is the most used drug of abuse worldwide. It is well established that the most
abundant phytocannabinoids in this plant are Δ9-tetrahydrocannabinol (THC) and …