Cannabis addiction and the brain: a review
Cannabis is the most commonly used substance of abuse in the United States after alcohol
and tobacco. With a recent increase in the rates of cannabis use disorder (CUD) and a …
and tobacco. With a recent increase in the rates of cannabis use disorder (CUD) and a …
Inflammation and the neural diathesis-stress hypothesis of schizophrenia: a reconceptualization
OD Howes, R McCutcheon - Translational psychiatry, 2017 - nature.com
An interaction between external stressors and intrinsic vulnerability is one of the longest
standing pathoaetiological explanations for schizophrenia. However, novel lines of evidence …
standing pathoaetiological explanations for schizophrenia. However, novel lines of evidence …
[HTML][HTML] Modulation of myelopoiesis progenitors is an integral component of trained immunity
I Mitroulis, K Ruppova, B Wang, LS Chen, M Grzybek… - Cell, 2018 - cell.com
Trained innate immunity fosters a sustained favorable response of myeloid cells to a
secondary challenge, despite their short lifespan in circulation. We thus hypothesized that …
secondary challenge, despite their short lifespan in circulation. We thus hypothesized that …
Endocannabinoid signalling and the deteriorating brain
V Di Marzo, N Stella, A Zimmer - Nature Reviews Neuroscience, 2015 - nature.com
Ageing is characterized by the progressive impairment of physiological functions and
increased risk of developing debilitating disorders, including chronic inflammation and …
increased risk of developing debilitating disorders, including chronic inflammation and …
Cerebellar dopamine D2 receptors regulate social behaviors
L Cutando, E Puighermanal, L Castell, P Tarot… - Nature …, 2022 - nature.com
The cerebellum, a primary brain structure involved in the control of sensorimotor tasks, also
contributes to higher cognitive functions including reward, emotion and social interaction …
contributes to higher cognitive functions including reward, emotion and social interaction …
The neural substrate of reward anticipation in health: a meta-analysis of fMRI findings in the monetary incentive delay task
The monetary incentive delay task breaks down reward processing into discrete stages for
fMRI analysis. Here we look at anticipation of monetary gain and loss contrasted with neutral …
fMRI analysis. Here we look at anticipation of monetary gain and loss contrasted with neutral …
Infectious immunity in the central nervous system and brain function
RS Klein, C Garber, N Howard - Nature immunology, 2017 - nature.com
Inflammation is emerging as a critical mechanism underlying neurological disorders of
various etiologies, yet its role in altering brain function as a consequence of neuroinfectious …
various etiologies, yet its role in altering brain function as a consequence of neuroinfectious …
Microglia in neuroimmunopharmacology and drug addiction
H Li, LR Watkins, X Wang - Molecular Psychiatry, 2024 - nature.com
Drug addiction is a chronic and debilitating disease that is considered a global health
problem. Various cell types in the brain are involved in the progression of drug addiction …
problem. Various cell types in the brain are involved in the progression of drug addiction …
Genome-wide association study implicates CHRNA2 in cannabis use disorder
Cannabis is the most frequently used illicit psychoactive substance worldwide; around one
in ten users become dependent. The risk for cannabis use disorder (CUD) has a strong …
in ten users become dependent. The risk for cannabis use disorder (CUD) has a strong …
THC and CBD: villain versus hero? Insights into adolescent exposure
Cannabis is the most used drug of abuse worldwide. It is well established that the most
abundant phytocannabinoids in this plant are Δ9-tetrahydrocannabinol (THC) and …
abundant phytocannabinoids in this plant are Δ9-tetrahydrocannabinol (THC) and …