Neuronal cell cultures have been used as an essential tool for studying pathomechanisms of
toxicity of chemotherapeutic drugs and to develop neuroprotective approaches. They offer …

Dissociated primary sensory neurons are commonly used to study growth factor–dependent
cell survival, axon outgrowth, differentiation and basic mechanisms of sensory physiology …

Efficient and homogeneous in vitro generation of peripheral sensory neurons may provide a
framework for novel drug screening platforms and disease models of touch and pain. We …

Background Dorsal root ganglion neuron-derived immortal cell lines including ND7/23 and F-
11 cells have been used extensively as in vitro model systems of native peripheral sensory …

The tumour mass is composed not only of heterogeneous neoplastic cells, but also a variety
of other components that may affect cancer cells behaviour. The lack of detailed knowledge …

Brain‐derived neurotrophic factor (BDNF) is implicated in the regulation of adult
hippocampal neurogenesis, presumably via its primary receptor, TrkB. However, controversy …

In the mouse trigeminal pathway, sensory inputs from distinct facial structures, such as
whiskers or lower jaw and lip, are topographically mapped onto the somatosensory cortex …

Introduction Chemotherapy induced peripheral neurotoxicity (CIPN) is a long-lasting, or
even permanent, late toxicity caused by largely used anticancer drugs. CIPN affects a …

In previous studies, stimulation of ionotropic AMPA/kainate glutamate receptors on cultured
oligodendrocyte cells induced the formation of a signaling complex that includes the AMPA …

Inflammation is part of the physiological wound healing response following mechanical
lesioning of the peripheral nervous system. However, cytokine effects on axonal …