Autophagy is a basic physiological process maintaining cell renewal, the degradation of
dysfunctional organelles, and the clearance of abnormal proteins and has recently been …

Lysosomal dysfunction is an essential pathogenesis of autophagic neuronal injury after
ischemic stroke. As a result of cerebral ischemia, transcription factor EB (TFEB) is greatly …

Autophagic/lysosomal dysfunction is a critical pathogenesis of neuronal injury after ischemic
stroke. Trehalose has been validated to restore the impaired autophagy flux by boosting …

Hyperhomocysteinemia is an independent risk factor for atherosclerosis. It is known that
macrophage autophagy plays a protective role in atherosclerosis and that …

Transcription factor EB (TFEB) is an important endogenous defensive protein that responds
to ischemic stimuli. Acute ischemic stroke is a growing concern due to its high morbidity and …

Autophagy is a process leading to the degradation of cellular material, in organelles called
lysosomes, to supply energy or generate building blocks for the synthesis of new materials …

Multiple sclerosis (MS) is a debilitating neurological disorder characterized by autoimmune-
driven demyelination within the central nervous system (CNS). Impaired remyelination …

Breast cancer is the most common type of cancer in the world. The aggressive and invasive
nature of these tumors is explicable by the presence of cancer stem cells, which have self …