[HTML][HTML] Recent Advancements in High-Frequency Ultrasound Applications from Imaging to Microbeam Stimulation

MG Kim, C Yoon, HG Lim - Sensors, 2024 - mdpi.com
Ultrasound is a versatile and well-established technique using sound waves with
frequencies higher than the upper limit of human hearing. Typically, therapeutic and …

Single-beam Acoustic Tweezers for Cell Biology: Molecular to in vivo level

J Yoo, J Ahn, H Ha, JC Jonas, C Kim… - IEEE Transactions on …, 2024 - ieeexplore.ieee.org
Acoustic tweezers have attracted attention in various fields of cell biology, including in vitro
single-cell and intercellular mechanics. Compared with other tweezing technologies such as …

[HTML][HTML] Role of actin-binding proteins in the regulation of cellular mechanics

AV Vakhrusheva, AV Murashko, ES Trifonova… - European Journal of …, 2022 - Elsevier
The viscoelastic parameters of the cell can report on the cell state, cellular processes and
diseases. Cell mechanics strongly rely on the properties of the cytoskeleton, an important …

Theory of pressure acoustics with viscous boundary layers and streaming in curved elastic cavities

JS Bach, H Bruus - The Journal of the Acoustical Society of America, 2018 - pubs.aip.org
The acoustic fields and streaming in a confined fluid depend strongly on the viscous
boundary layer forming near the wall. The width of this layer is typically much smaller than …

Whole-system ultrasound resonances as the basis for acoustophoresis in all-polymer microfluidic devices

RP Moiseyenko, H Bruus - Physical Review Applied, 2019 - APS
Using a previously-well-tested numerical model, we demonstrate that good acoustophoresis
can be obtained in a microchannel embedded in an acoustically soft, all-polymer chip by …

Automated cell-type classification combining dilated convolutional neural networks with label-free acoustic sensing

HJ Jeon, HG Lim, KK Shung, OJ Lee, MG Kim - Scientific Reports, 2022 - nature.com
This study aimed to automatically classify live cells based on their cell type by analyzing the
patterns of backscattered signals of cells with minimal effect on normal cell physiology and …

Automated estimation of cancer cell deformability with machine learning and acoustic trapping

OJ Lee, HG Lim, KK Shung, JT Kim, HH Kim - Scientific Reports, 2022 - nature.com
Cell deformability is a useful feature for diagnosing various diseases (eg, the invasiveness
of cancer cells). Existing methods commonly inflict pressure on cells and observe changes …

Investigation of cell mechanics using single-beam acoustic tweezers as a versatile tool for the diagnosis and treatment of highly invasive breast cancer cell lines: an in …

HG Lim, HC Liu, CW Yoon, H Jung, MG Kim… - Microsystems & …, 2020 - nature.com
Advancements in diagnostic systems for metastatic cancer over the last few decades have
played a significant role in providing patients with effective treatment by evaluating the …

Three-dimensional numerical modeling of acoustic trapping in glass capillaries

MWH Ley, H Bruus - Physical Review Applied, 2017 - APS
Acoustic traps are used to capture and handle suspended microparticles and cells in
microfluidic applications. A particular simple and much-used acoustic trap consists of a …

Quantification of inter-erythrocyte forces with ultra-high frequency (410 MHz) single beam acoustic tweezer

HG Lim, KK Shung - Annals of biomedical engineering, 2017 - Springer
Efforts on quantitative measurements of the interactive forces of red blood cells (RBC) have
been pursued for many years in hopes of a better understanding of hemodynamics and …