Streptozotocin‐induced diabetes models: Pathophysiological mechanisms and fetal outcomes

DC Damasceno, AO Netto, IL Iessi… - BioMed research …, 2014 - Wiley Online Library
Glucose homeostasis is controlled by endocrine pancreatic cells, and any pancreatic
disturbance can result in diabetes. Because 8% to 12% of diabetic pregnant women present …

Biomaterials and advanced technologies for the evaluation and treatment of ovarian aging

M Wu, Y Guo, S Wei, L Xue, W Tang, D Chen… - Journal of …, 2022 - Springer
Ovarian aging is characterized by a progressive decline in ovarian function. With the
increase in life expectancy worldwide, ovarian aging has gradually become a key health …

Experimental diabetes impairs maternal reproductive performance in pregnant Wistar rats and their offspring

L Bequer, T Gómez, JL Molina, A Álvarez… - Systems biology in …, 2018 - Taylor & Francis
The aim of this study was to determine the effect of mild hyperglycemia on metabolism
during pregnancy, the maternal reproductive performance, and the characteristics of the …

Propolis improves pregnancy outcomes and placental oxidative stress status in streptozotocin-induced diabetic rats

UZ Usman, ABA Bakar, M Mohamed - BMC complementary and …, 2018 - Springer
Background This study assessed the effects of propolis alone or combined with insulin on
maternal status, pregnancy outcomes and placental oxidative stress in streptozotocin …

Chronic moderate hyperglycemia does not alter sexual motivation in the female rat

AK Hernández-Munive, A Fernández-Guasti - Physiology & Behavior, 2024 - Elsevier
The relationship between diabetes mellitus type 2 (DM2) and sexual desire in women has
not been systematically studied, therefore, animal models have been used for this purpose …

Placental angiogenic and hormonal factors are affected by thyroid hormones in rats

JF Silva, NM Ocarino, R Serakides - Pathology-Research and Practice, 2015 - Elsevier
The objective of the present study was to evaluate the effect of the thyroid hormones in the
gene transcription and immunohistochemical expression of hormonal and angiogenic …

[HTML][HTML] Acción de la estreptozotocina en un modelo experimental de inducción neonatal de la diabetes

L Bequer, T Gómez, JL Molina, D Artiles, R Bermúdez… - Biomédica, 2016 - scielo.org.co
Introducción. El estudio de la diabetes mediante modelos experimentales es fundamental
para entender los mecanismos fisiopatológicos de la enfermedad. Objetivos. Comparar en …

Pulmonary impairment in type 2 diabetic rats and its improvement by exercise

LMQ Machado, DS Serra, TG Neves… - Acta …, 2022 - Wiley Online Library
Aim We aimed to evaluate whether the streptozotocin‐induced diabetic model can generate
lung functional, histological and biochemical impairments and whether moderate exercise …

Diabetes mellitus and female sexual response: what do animal models tell us?

AK Hernández-Munive… - Sexual Medicine …, 2024 - academic.oup.com
Background One of the less explored effects of diabetes mellitus (DM) is female sexual
dysfunction. Females of different species have been used as models. Aim To analyze the …

[HTML][HTML] Effects of snack intake during pregnancy and lactation on reproductive outcome in mild hyperglycemic rats

MG Martins, AG da Cruz, GP de Oliveira… - Physiology & …, 2021 - Elsevier
Metabolic disorders, like diabetes, as well as maternal diet, alter nutrient availability in utero,
inducing adaptations in the offspring. Whether the effects of maternal hyperglycemia are …