Injectable hydrogels can provide a scaffold for in situ tissue regrowth and regeneration, yet
gel degradation before tissue reformation limits the gels' ability to provide physical support …

The central nervous system (CNS) can be injured or damaged through a variety of insults
including traumatic injury, stroke, and neurodegenerative or demyelinating diseases …

Huntington's disease (HD) is an inherited neurodegenerative disorder caused by the
abnormal expansion of CAG trinucleotide repeats in the Huntingtin gene (HTT) located on …

Cell transplantation is an effective strategy to improve the repair effect of nerve guide
conduits (NGCs). However, problems such as low loading efficiency and cell anoikis …

Highly macroporous semi-synthetic cryogel microcarriers could be synthesized for culturing
stem cells and neuronal type cells. Growth factors loaded to the heparin containing …

The dopamine precursor, levodopa, remains the “gold standard” treatment for Parkinson's
disease, and, although it provides superlative efficacy in the early stages of the disease, its …

We present the synthesis of hydrogel microbeads based on telechelic poly (2-
oxazoline)(POx) crosslinkers and the methacrylate monomers (HEMA, METAC, SPMA) by …

Parkinson's disease (PD) is characterized by a progressive loss of dopaminergic neurons
and represents a growing health burden to western societies. Like many neurodegenerative …

An increasing number of in vivo and in vitro neuro-engineering applications are making use
of colloidal particles as neuronal cell carriers. Recent studies highlight the shortcomings of …

Successful cell replacement therapy in the central nervous system (CNS) depends on both
the transplanted cell type and the cell delivery method. It was established that differentiated …