Background miRNAs, a class of small endogenous RNAs, are one of the essential
biopharmaceuticals which are in commercial spans as next-generation medicine in recent …

Capillary electrophoresis is recognized as a valued separation technique for its high
separation efficiency, low sample consumption, good economic and ecological aspects …

Accurate, sensitive, and highly selective detection of biological targets is of great
significance in a wide range of domains, including clinical diagnosis, disease therapy, drug …

Acquiring accurate and reliable results are crucial in pharmaceutical and biomedical
analyses. There is a demand for the ongoing development and validation of advanced …

Bioanalytical methods, based on a variety of physico-chemical and biological techniques
such as chromatography, immunoassay and mass spectrometry, must be validated prior to …

Derivatization, or chemical structure modification, is often used in bioanalysis performed by
liquid chromatography technique in order to enhance detectability or to improve the …

Drug discovery and development involves a complex iterative process of new molecules
synthesis, formulations, and in vitro analysis, followed by biochemical and cellular assays …

A variety of imaging techniques are available for detecting biological processes with
sufficient penetration depth and temporal resolution. However, inflammation, cardiovascular …

Liquid chromatography-tandem mass spectrometry-based bioanalytical procedures are a
group of highly versatile and ultra-sensitive analytical technique that plays a critical role in …

Abstract Scientifically qualified LC–MS/MS methods are essential for the determination of
small molecule drug candidates and/or their metabolite (s) in support of various non …