2021 MAGNIMS–CMSC–NAIMS consensus recommendations on the use of MRI in patients with multiple sclerosis

MP Wattjes, O Ciccarelli, DS Reich, B Banwell… - The Lancet …, 2021 - thelancet.com
Summary The 2015 Magnetic Resonance Imaging in Multiple Sclerosis and 2016
Consortium of Multiple Sclerosis Centres guidelines on the use of MRI in diagnosis and …

Vitamin D and immunity in infants and children

G Mailhot, JH White - Nutrients, 2020 - mdpi.com
The last couple of decades have seen an explosion in our interest and understanding of the
role of vitamin D in the regulation of immunity. At the molecular level, the hormonal form of …

Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS

MA Gianfrancesco, P Stridh, B Rhead, X Shao, E Xu… - Neurology, 2017 - AAN Enterprises
Objective: To utilize Mendelian randomization to estimate the causal association between
low serum vitamin D concentrations, increased body mass index (BMI), and pediatric-onset …

Diagnostic algorithm for relapsing acquired demyelinating syndromes in children

Y Hacohen, K Mankad, WK Chong, F Barkhof… - Neurology, 2017 - AAN Enterprises
Objective: To establish whether children with relapsing acquired demyelinating syndromes
(RDS) and myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) show distinctive …

Clinical characteristics and disability progression of early-and late-onset multiple sclerosis compared to adult-onset multiple sclerosis

O Mirmosayyeb, S Brand, M Barzegar… - Journal of clinical …, 2020 - mdpi.com
Background: Compared to the adult onset of multiple sclerosis (AOMS), both early-onset
(EOMS) and late-onset (LOMS) are much less frequent, but are often under-or …

MOGAD: how it differs from and resembles other neuroinflammatory disorders

M Shahriari, ES Sotirchos… - American Journal of …, 2021 - Am Roentgen Ray Soc
Myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) is a distinct
CNS inflammatory disease with symptoms and imaging findings that overlap other …

Effects of orally administered cannabidiol on neuroinflammation and intestinal inflammation in the attenuation of experimental autoimmune encephalomyelitis

N Dopkins, K Miranda, K Wilson, BL Holloman… - Journal of Neuroimmune …, 2021 - Springer
Cannabidiol (CBD) is a bioactive compound isolated from Cannabis plants that has
garnered attention within the medical community due to its potent anti-inflammatory …

Aggressive multiple sclerosis (1): Towards a definition of the phenotype

E Iacobaeus, G Arrambide, MP Amato… - Multiple Sclerosis …, 2020 - journals.sagepub.com
While the major phenotypes of multiple sclerosis (MS) and relapsing–remitting, primary and
secondary progressive MS have been well characterized, a subgroup of patients with an …

Epidemiology of pediatric multiple sclerosis: A systematic literature review and meta-analysis

K Yan, C Balijepalli, K Desai, L Gullapalli… - Multiple sclerosis and …, 2020 - Elsevier
Background Multiple sclerosis (MS) is a debilitating immune disease leading to
demyelination, neurodegeneration, and chronic inflammation of the central nervous system …

Gut microbiome is associated with multiple sclerosis activity in children

MK Horton, K McCauley, D Fadrosh… - Annals of clinical …, 2021 - Wiley Online Library
Objective To identify features of the gut microbiome associated with multiple sclerosis
activity over time. Methods We used 16S ribosomal RNA sequencing from stool of 55 …