Flavonoids are polyphenolic compounds subdivided into 6 groups: isoflavonoids,
flavanones, flavanols, flavonols, flavones and anthocyanidins found in a variety of plants …

Apoptosis or programmed cell death is natural way of removing aged cells from the body.
Most of the anti-cancer therapies trigger apoptosis induction and related cell death networks …

Green tea is rich in polyphenol flavonoids including catechins. Epigallocatechin 3-gallate
(EGCG) is the most abundant and potent green tea catechin. EGCG has been extensively …

Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

Tea, a popular beverage made from leaves of the plant Camellia sinensis, has been shown
to reduce body weight, alleviate metabolic syndrome, and prevent diabetes and …

Cancer arises in the context of an in vivo tumor microenvironment. This microenvironment is
both a cause and consequence of tumorigenesis. Tumor and host cells co-evolve …

In aging and neurodegenerative diseases, loss of distinct type of neurons characterizes
disease-specific pathological and clinical features, and mitochondria play a pivotal role in …

Doxorubicin (Dox)‐mediated generation of reactive oxygen radicals (ROS) for mitochondrial
apoptosis is identified as a new cytotoxic mechanism in addition to the well‐established one …

Tea, a popular beverage made from leaves of the plant Camellia sinensis, has been studied
extensively in recent decades for its beneficial health effects in the prevention of obesity …

Abstract Epigallocatechin-3-gallate (EGCG) is a type of catechin found in green tea. EGCG
exhibits a variety of activities, including anti-inflammatory, antidiabetes, antiobesity, and …