Glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis

M Tan, Y Yin, X Ma, J Zhang, W Pan, M Tan… - Cell Death & …, 2023 - nature.com
The glutathione (GSH) system is considered to be one of the most powerful endogenous
antioxidant systems in the cardiovascular system due to its key contribution to detoxifying …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Curcumin nanoparticles as promising therapeutic agents for drug targets

H Chopra, PS Dey, D Das, T Bhattacharya, M Shah… - Molecules, 2021 - mdpi.com
Curcuma longa is very well-known medicinal plant not only in the Asian hemisphere but also
known across the globe for its therapeutic and medicinal benefits. The active moiety of …

Antiviral and immunomodulatory activity of curcumin: A case for prophylactic therapy for COVID-19

RK Thimmulappa, KK Mudnakudu-Nagaraju… - Heliyon, 2021 - cell.com
Abstract Coronavirus disease-19 (COVID-19), a devastating respiratory illness caused by
SARS-associated coronavirus-2 (SARS-CoV-2), has already affected over 64 million people …

Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults: A GRADE-assessed systematic review and dose–response meta-analysis of …

MJ Dehzad, H Ghalandari, M Nouri, M Askarpour - Cytokine, 2023 - Elsevier
Turmeric and its prominent bioactive compound, curcumin, have been the subject of many
investigations with regard to their impact on inflammatory and oxidative balance in the body …

[HTML][HTML] A systematic review on advances in management of oxidative stress-associated cardiovascular diseases

S Jin, PM Kang - Antioxidants, 2024 - mdpi.com
Oxidative stress plays a significant role in the pathogenesis of cardiovascular diseases, such
as myocardial ischemia/reperfusion injury, atherosclerosis, heart failure, and hypertension …

Effect of nano‐curcumin on various diseases: a comprehensive review of clinical trials

S Hassanizadeh, M Shojaei, M Bagherniya… - Biofactors, 2023 - Wiley Online Library
The antioxidant, anti‐inflammatory, and antibacterial properties of curcumin have made it a
valuable herbal product for improving various disorders, such as COVID‐19, cancer …

Three months of combination therapy with nano‐curcumin reduces the inflammation and lipoprotein (a) in type 2 diabetic patients with mild to moderate coronary …

M Dastani, HR Rahimi, VR Askari, MR Jaafari… - Biofactors, 2023 - Wiley Online Library
Diabetes is one of the most common chronic diseases worldwide. Systemic inflammation
(high‐sensitivity C‐reactive protein (hs‐CRP)) and lipid metabolism disruption (lipoprotein …

Curcumin as a natural remedy for atherosclerosis: a pharmacological review

L Singh, S Sharma, S Xu, D Tewari, J Fang - Molecules, 2021 - mdpi.com
Curcumin, a natural polyphenolic compound present in Curcuma longa L. rhizomes, shows
potent antioxidant, anti-inflammatory, anti-cancer, and anti-atherosclerotic properties …

Nano‐Derived Therapeutic Formulations with Curcumin in Inflammation‐Related Diseases

C Quispe, N Cruz-Martins, ML Manca… - Oxidative Medicine …, 2021 - Wiley Online Library
Due to its vast therapeutic potential, the plant‐derived polyphenol curcumin is utilized in an
ever‐growing number of health‐related applications. Here, we report the extraction …