Early switch from intravenous to oral antibiotic treatment in bone and joint infections

P Sendi, J Lora-Tamayo, NW Cortes-Penfield… - Clinical Microbiology and …, 2023 - Elsevier
Objectives The timing of the switch from intravenous (iv) to oral antibiotic therapy for
orthopaedic bone and joint infections (BJIs) is debated. In this narrative article, we discuss …

Taking the route less traveled: on the way to COpAT

M Pertzborn, CG Rivera… - Therapeutic Advances in …, 2023 - journals.sagepub.com
Antimicrobial therapy is an essential practice within medicine. Over the last 4 years, complex
outpatient antimicrobial therapy (COpAT) with oral antimicrobials has become a rapidly …

Early-Outcome Differences between Acute and Chronic Periprosthetic Joint Infections—A Retrospective Single-Center Study

Y Youssef, E Roschke, N Dietze, AJ Dahse… - Antibiotics, 2024 - mdpi.com
Periprosthetic joint infections (PJI) are serious complications after arthroplasty, associated
with high morbidity, mortality, and complex treatment processes. The outcomes of different …

Safety and effectiveness of fifth generation cephalosporins for the treatment of methicillin-resistant staphylococcus aureus bloodstream infections: a narrative review …

DF Bavaro, A Belati, L Bussini, V Cento… - Expert Opinion on …, 2024 - Taylor & Francis
ABSTRACT Introduction Methicillin-resistant Staphylococcus aureus (MRSA) bloodstream
infection (BSI) is a major issue in healthcare, since it is often associated with endocarditis or …

[HTML][HTML] How are Oral Antibiotics Being Used in Total Joint Arthroplasty? A Review of the Literature

TR Weiner, DB El-Najjar, CL Herndon… - Orthopedic …, 2024 - ncbi.nlm.nih.gov
While the role and benefit of perioperative intravenous (IV) antibiotics in patients undergoing
total joint arthroplasty (TJA) is well-established, oral antibiotic use in TJA remains a …

Sex-related differences in periprosthetic joint infection research

D De Mauro, C Meschini, G Balato… - Journal of Bone and …, 2024 - jbji.copernicus.org
Abstract Introduction: Periprosthetic joint infections (PJIs) have emerged as a focal point in
the realm of orthopedics, garnering widespread attention owing to the escalating incidence …

The Incidence Rate, Microbiological Etiology, and Results of Treatments of Prosthetic Joint Infection following Total Knee Arthroplasty

HK Yoon, JH Yoo, HC Oh, JW Ha, SH Park - Journal of Clinical Medicine, 2023 - mdpi.com
Periprosthetic joint infection (PJI) remains among the most challenging and costly
complications. PJI rates vary from 0.39% to 3.9% after total knee arthroplasty (TKA). This …

Microbiological Profile and Drug Resistance in Bone and Joint Infections: A Survey in Orthopedic Wards of a Great Referral Hospital in Tehran, Iran

S Salarvand, A Abdollahi, M Doraghi… - Jundishapur Journal of …, 2023 - brieflands.com
Background: Patients undergoing orthopedic surgery are at risk of nosocomial infections,
and antibiotic resistance is known to increase the risk of such infections. Objectives: We …

Multisite Study of the Management of Musculoskeletal Infection After Trauma: The MMUSKIT Study

J Seidelman, AS Ritter, E Poehlein… - Open Forum …, 2024 - academic.oup.com
Background The optimal duration and choice of antibiotic for fracture-related infection (FRI)
is not well defined. This study aimed to determine whether antibiotic duration (≤ 6 vs> 6 …

[HTML][HTML] Wide Geographic Variation in Resource Utilization after Shoulder Arthroplasty

S Sudah, M Menendez, A Jawa, J Levy… - Orthopedic …, 2023 - ncbi.nlm.nih.gov
Background There is growing interest in optimizing cost and resource utilization after
shoulder arthroplasty, but little data to guide improvement efforts. Objective The purpose of …