microRNAs are small non-coding RNAs that regulate several genes post-transcriptionally by
complementarity pairing. Since discovery, they have been reported to be involved in a …

Alterations in microRNAs (miRNAs) expression are causative in the initiation and
progression of human cancers. The molecular events responsible for the widespread …

Clinical and experimental evidence has shown that tumor-associated macrophages promote
cancer initiation and progression. However, the macrophage-derived molecular …

Breast cancer (BC) is the most common cancer in women and poses a serious threat to their
health. Despite familiarity with factors affecting its etiology, initiation, progression, treatment …

The epithelial-mesenchymal transition (EMT) represents a biological program during which
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …

Human diseases have always been a significant turf of concern since the origin of mankind.
It is cardinal to know the cause, treatment, and cure for every disease condition. With the …

Exosomes, ranging in size from 30 to 150 nm as identified initially via electron microscopy in
1946, are one of the extracellular vesicles (EVs) produced by many cells and have been the …

Advanced ovarian cancer usually spreads to the visceral adipose tissue of the omentum.
However, the omental stromal cell-derived molecular determinants that modulate ovarian …

CRISPR-based diagnostics (CRISPR-Dx) has shown great promise in molecular
diagnostics, but its utility in the sensing of microRNA (miRNA) biomarkers is limited by …

Chemotherapy has been widely applied in clinics. However, the therapeutic potential of
chemotherapy against cancer is seriously dissatisfactory due to the nonspecific drug …