Mesenchymal stem cells for neurological disorders
A Andrzejewska, S Dabrowska, B Lukomska… - Advanced …, 2021 - Wiley Online Library
Neurological disorders are becoming a growing burden as society ages, and there is a
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …
Mesenchymal stromal cell therapies for neurodegenerative diseases
Mesenchymal stromal cells are multipotent cells that are being used to treat a variety of
medical conditions. Over the past decade, there has been considerable excitement about …
medical conditions. Over the past decade, there has been considerable excitement about …
Mesenchymal stromal cells (MSCs) for neurodegenerative disease: a promising frontier
A Shariati, R Nemati, Y Sadeghipour… - European journal of cell …, 2020 - Elsevier
Neurodegenerative disorders are a variety of diseases including Alzheimer's (AD),
Parkinson's (PD), and Huntington's diseases (HD), multiple sclerosis (MS) and amyotrophic …
Parkinson's (PD), and Huntington's diseases (HD), multiple sclerosis (MS) and amyotrophic …
A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse
Background Chronic neuroinflammation, aggressive amyloid beta (Aβ) deposition, neuronal
cell loss, and cognitive impairment are pathological presentations of Alzheimer's disease …
cell loss, and cognitive impairment are pathological presentations of Alzheimer's disease …
Effect of systemic transplantation of bone marrow‐derived mesenchymal stem cells on neuropathology markers in APP/PS 1 Alzheimer mice
Y Naaldijk, C Jaeger, C Fabian… - Neuropathology and …, 2017 - Wiley Online Library
Aims Mesenchymal stem cells (MSC) have recently attracted interest as a potential basis for
a cell‐based therapy of AD. We investigated the putative immune‐modulatory effects in …
a cell‐based therapy of AD. We investigated the putative immune‐modulatory effects in …
Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease
JY Lee, SH Han, MH Park, B Baek, IS Song… - Nature …, 2018 - nature.com
Although many reports have revealed the importance of defective microglia-mediated
amyloid β phagocytosis in Alzheimer's disease (AD), the underlying mechanism remains to …
amyloid β phagocytosis in Alzheimer's disease (AD), the underlying mechanism remains to …
Stem cell therapy for Alzheimer's disease: An overview of experimental models and reality
C Qin, K Wang, L Zhang, L Bai - Animal models and …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative disorder. The pathology of AD is
characterized by extracellular amyloid beta (Aβ) plaques, neurofibrillary tangles composed …
characterized by extracellular amyloid beta (Aβ) plaques, neurofibrillary tangles composed …
Placenta-derived mesenchymal stem cells improve memory dysfunction in an Aβ1–42-infused mouse model of Alzheimer's disease
HM Yun, HS Kim, KR Park, JM Shin, AR Kang… - Cell death & …, 2013 - nature.com
Mesenchymal stem cells (MSCs) promote functional recoveries in pathological experimental
models of central nervous system (CNS) and are currently being tested in clinical trials for …
models of central nervous system (CNS) and are currently being tested in clinical trials for …
The functional mechanism of bone marrow-derived mesenchymal stem cells in the treatment of animal models with Alzheimer's disease: crosstalk between autophagy …
C Qin, L Bai, Y Li, K Wang - Stem cell research & therapy, 2022 - Springer
The transplantation of bone marrow-derived mesenchymal stem cells (BMMSCs) alleviates
neuropathology and improves cognitive deficits in animal models with Alzheimer's disease …
neuropathology and improves cognitive deficits in animal models with Alzheimer's disease …
Clinical PET imaging of microglial activation: implications for microglial therapeutics in Alzheimer's disease
Z Shen, X Bao, R Wang - Frontiers in aging neuroscience, 2018 - frontiersin.org
In addition to extracellular β-amyloid plaques and intracellular neurofibrillary tangles,
neuroinflammation has been identified as a key pathological characteristic of Alzheimer's …
neuroinflammation has been identified as a key pathological characteristic of Alzheimer's …