Chronic wounds: Current status, available strategies and emerging therapeutic solutions

K Las Heras, M Igartua, E Santos-Vizcaino… - Journal of controlled …, 2020 - Elsevier
In the past decades, adequate and well-planned management of chronic wounds has
reached an elevated importance to improve human's quality of life and extend life …

Placental tissues as biomaterials in regenerative medicine

A Roy, M Mantay, C Brannan… - BioMed Research …, 2022 - Wiley Online Library
Placental tissues encompass all the tissues which support fetal development, including the
placenta, placental membrane, umbilical cord, and amniotic fluid. Since the 1990s there has …

Mesenchymal stromal cells and their secretome: new therapeutic perspectives for skeletal muscle regeneration

M Sandonà, L Di Pietro, F Esposito… - … in bioengineering and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are multipotent cells found in different tissues: bone
marrow, peripheral blood, adipose tissues, skeletal muscle, perinatal tissues, and dental …

Engineered biopolymeric scaffolds for chronic wound healing

LE Dickinson, S Gerecht - Frontiers in physiology, 2016 - frontiersin.org
Skin regeneration requires the coordinated integration of concomitant biological and
molecular events in the extracellular wound environment during overlapping phases of …

Placenta and placental derivatives in regenerative therapies: experimental studies, history, and prospects

O Pogozhykh, V Prokopyuk, C Figueiredo… - Stem cells …, 2018 - Wiley Online Library
Placental structures, capable to persist in a genetically foreign organism, are a natural
model of allogeneic engraftment carrying a number of distinctive properties. In this review …

Autophagy: a potential key contributor to the therapeutic action of mesenchymal stem cells

S Ceccariglia, A Cargnoni, AR Silini, O Parolini - Autophagy, 2020 - Taylor & Francis
Macroautophagy/autophagy occurs at basal levels in all eukaryotic cells and plays an
important role in maintaining bio-energetic homeostasis through the control of molecule …

Perinatal derivatives: where do we stand? A roadmap of the human placenta and consensus for tissue and cell nomenclature

AR Silini, R Di Pietro, I Lang-Olip, F Alviano… - … in bioengineering and …, 2020 - frontiersin.org
Progress in the understanding of the biology of perinatal tissues has contributed to the
breakthrough revelation of the therapeutic effects of perinatal derivatives (PnD), namely birth …

Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model

Y Lu, J Zhang, F Zeng, P Wang, X Guo, H Wang… - Journal of …, 2022 - Springer
Abstract Background Mesenchymal stem cell (MSCs)-derived small Extracellular Vesicles
(sEVs) are considered as a new cell-free therapy for pain caused by nerve injury, but …

The immunomodulatory properties of amniotic cells: the two sides of the coin

M Magatti, E Vertua, A Cargnoni, A Silini… - Cell …, 2018 - journals.sagepub.com
Among the many cell types useful in developing therapeutic treatments, human amniotic
cells from placenta have been proposed as valid candidates. Both human amniotic epithelial …

Human amniotic mesenchymal stem cells to promote/suppress cancer: two sides of the same coin

A Jafari, M Rezaei-Tavirani… - Stem Cell Research & …, 2021 - Springer
Cancer is a leading cause of death in both developed and developing countries, and
because of population growth and aging, it is a growing medical burden worldwide. With …