Crosstalk between circRNAs and the PI3K/AKT signaling pathway in cancer progression

C Xue, G Li, J Lu, L Li - Signal transduction and targeted therapy, 2021 - nature.com
Circular RNAs (circRNAs), covalently closed noncoding RNAs, are widely expressed in
eukaryotes and viruses. They can function by regulating target gene expression, linear RNA …

Barriers and strategies of cationic liposomes for cancer gene therapy

C Liu, L Zhang, W Zhu, R Guo, H Sun, X Chen… - … Therapy Methods & …, 2020 - cell.com
Cationic liposomes (CLs) have been regarded as the most promising gene delivery vectors
for decades with the advantages of excellent biodegradability, biocompatibility, and high …

Co-loading of inorganic nanoparticles and natural oil in the electrospun janus nanofibers for a synergetic antibacterial effect

M Wang, DG Yu, GR Williams, SWA Bligh - Pharmaceutics, 2022 - mdpi.com
Side-by-side electrospinning is a powerful but challenging technology that can be used to
prepare Janus nanofibers for various applications. In this work, cellulose acetate (CA) and …

Recent progress of RGD modified liposomes as multistage rocket against cancer

A Sheikh, NA Alhakamy, S Md… - Frontiers in …, 2022 - frontiersin.org
Cancer is a life-threatening disease, contributing approximately 9.4 million deaths
worldwide. To address this challenge, scientific researchers have investigated molecules …

Dual-targeting and stimuli-triggered liposomal drug delivery in cancer treatment

N AlSawaftah, WG Pitt, GA Husseini - ACS pharmacology & …, 2021 - ACS Publications
The delivery of chemotherapeutics to solid tumors using smart drug delivery systems
(SDDSs) takes advantage of the unique physiology of tumors (ie, disordered structure, leaky …

Tumor cell-induced platelet aggregation as an emerging therapeutic target for cancer therapy

W Strasenburg, J Jóźwicki, J Durślewicz… - Frontiers in …, 2022 - frontiersin.org
Tumor cells have the ability to induce platelet activation and aggregation. This has been
documented to be involved in tumor progression in several types of cancers, such as lung …

Recent advances in liposome-based targeted cancer therapy

Y Fidan, S Muçaj, SS Timur… - Journal of Liposome …, 2024 - Taylor & Francis
Nano-drug delivery systems have opened new pathways for tumor treatment by overcoming
some of the limitations of conventional drugs, such as physiological degradation, short half …

Functional materials for subcellular targeting strategies in cancer therapy: progress and prospects

Y Cheng, Z Qu, Q Jiang, T Xu, H Zheng, P Ye… - Advanced …, 2023 - Wiley Online Library
Neoadjuvant and adjuvant therapies have made significant progress in cancer treatment.
However, tumor adjuvant therapy still faces challenges due to the intrinsic heterogeneity of …

[HTML][HTML] Robust strategies in nuclear-targeted cancer therapy based on functional nanomaterials

X Qin, H Zhang, X Xing, P Wang, J Yan, D Liu, Q Gong… - Materials & Design, 2022 - Elsevier
Nucleus, as the machinery for genome transcription, play prominent roles to support the
fundamental cellular functions, the destruction of any of these specific parts would …

Precisely Targeted Nano‐Controller of PD‐L1 Level for Non‐Small Cell Lung Cancer Spinal Metastasis Immunotherapy

L Zhou, H Liang, Y Ge, W Ding, Q Chen… - Advanced …, 2022 - Wiley Online Library
Although immune checkpoint inhibitors (ICIs) have been widely applied to treat non‐small
cell lung cancer (NSCLC), a significant proportion of patients, especially those with spinal …