The interactions of cell surface carbohydrates as well as of soluble glycoconjugates with
their receptor proteins rule fundamental processes in cell biology. One of the …

Pathogens including viruses, bacteria, fungi, and parasites continue to shape our lives in
profound ways every day. As we have learned to live in parallel with pathogens, we have …

Carbohydrates are important as signaling molecules and for cellular recognition events,
therefore offering scope for the development of carbohydrate-mimetic diagnostics and drug …

Lectins, a distinct group of glycan-binding proteins, play a prominent role in the immune
system ranging from pathogen recognition and tuning of inflammation to cell adhesion or …

This review comprehensively covers the most recent achievements (from 2013) in the
successful integration of nanomaterials in the field of glycomics. The first part of the paper …

Click chemistry was extensively used to decorate synthetic multivalent scaffolds with glycans
to mimic the cell surface glycocalyx and to develop applications in glycosciences …

Cyclopeptides have been recently used successfully as carriers for the multivalent
presentation of carbohydrate and peptide antigens in immunotherapy. Beside their synthetic …

Bacterial and fungal pathogens involved in lung infection in cystic fibrosis patients utilize a
particular family of glycan-binding proteins, characterized by the presentation of six fucose …

Multivalent structures displaying different instead of similar sugar units, namely
heteroglycoclusters (hGCs), are stimulating the efforts of glycochemists for developing …

Among other classes of biomolecules, carbohydrates and glycoconjugates are widely
involved in numerous biological functions. In addition to addressing the related synthetic …