Next-generation approaches to understand and combat the antibiotic resistome
Antibiotic resistance is a natural feature of diverse microbial ecosystems. Although recent
studies of the antibiotic resistome have highlighted barriers to the horizontal transfer of …
studies of the antibiotic resistome have highlighted barriers to the horizontal transfer of …
Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives
Antibiotic-resistant Mycobacterium tuberculosis strains are threatening progress in
containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …
containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …
[HTML][HTML] Antibiotic resistance in Vibrio cholerae: understanding the ecology of resistance genes and mechanisms
The unique genetic makeup and remarkable competency of Vibrio cholerae are the key
factors that help the cholera pathogen adapt rapidly to adverse environmental conditions …
factors that help the cholera pathogen adapt rapidly to adverse environmental conditions …
The evolution of antibiotic resistance is associated with collateral drug phenotypes in Mycobacterium tuberculosis
The increasing incidence of drug resistance in Mycobacterium tuberculosis has diminished
the efficacy of almost all available antibiotics, complicating efforts to combat the spread of …
the efficacy of almost all available antibiotics, complicating efforts to combat the spread of …
Molecular Targets Related Drug Resistance Mechanisms in MDR-, XDR-, and TDR-Mycobacterium tuberculosis Strains
HMA Hameed, MM Islam, C Chhotaray… - Frontiers in cellular …, 2018 - frontiersin.org
Tuberculosis (TB) is a formidable infectious disease that remains a major cause of death
worldwide today. Escalating application of genomic techniques has expedited the …
worldwide today. Escalating application of genomic techniques has expedited the …
Genomic insights into tuberculosis
JE Galagan - Nature Reviews Genetics, 2014 - nature.com
Prevalent since pre-history, human tuberculosis—caused by the pathogen Mycobacterium
tuberculosis—remains a major source of death worldwide. Moreover, increasing drug …
tuberculosis—remains a major source of death worldwide. Moreover, increasing drug …
Molecular diagnosis of drug-resistant tuberculosis; a literature review
Drug-resistant tuberculosis is a global health problem that hinders the progress of
tuberculosis eradication programs. Accurate and early detection of drug-resistant …
tuberculosis eradication programs. Accurate and early detection of drug-resistant …
Totally drug‐resistant tuberculosis and adjunct therapies
SK Parida, R Axelsson‐Robertson… - Journal of internal …, 2015 - Wiley Online Library
The first cases of totally drug‐resistant (TDR) tuberculosis (TB) were reported in Italy 10
years ago; more recently, cases have also been reported in Iran, India and South Africa …
years ago; more recently, cases have also been reported in Iran, India and South Africa …
Profiling pretomanid as a therapeutic option for TB infection: evidence to date
SL Stancil, F Mirzayev… - Drug Design …, 2021 - Taylor & Francis
Tuberculosis (TB) is the most deadly infectious disease globally. Although most individuals
achieve a cure, a substantial portion develop multi-drug resistant TB which is exceedingly …
achieve a cure, a substantial portion develop multi-drug resistant TB which is exceedingly …
[HTML][HTML] Strategies for lipid-based nanocomposites with potential activity against Mycobacterium tuberculosis: Microbial resistance challenge and drug delivery trends
AC Hatae, CA Roque-Borda, FR Pavan - OpenNano, 2023 - Elsevier
Mycobacterium tuberculosis (MTB), the causative agent of tuberculosis, stands as an
immensely devastating and persistently relevant pathogen, claiming the lives of millions …
immensely devastating and persistently relevant pathogen, claiming the lives of millions …