An overview of Nrf2 signaling pathway and its role in inflammation

S Saha, B Buttari, E Panieri, E Profumo, L Saso - Molecules, 2020 - mdpi.com
Inflammation is a key driver in many pathological conditions such as allergy, cancer,
Alzheimer's disease, and many others, and the current state of available drugs prompted …

[HTML][HTML] Nrf2 signaling pathway: Pivotal roles in inflammation

SMU Ahmed, L Luo, A Namani, XJ Wang… - Biochimica et Biophysica …, 2017 - Elsevier
Inflammation is the most common feature of many chronic diseases and complications, while
playing critical roles in carcinogenesis. Several studies have demonstrated that Nrf2 …

Benefits of hesperidin for cutaneous functions

MQ Man, B Yang, PM Elias - Evidence‐Based Complementary …, 2019 - Wiley Online Library
Hesperidin is a bioflavonoid, with high concentration in citrus fruits. In addition to its well‐
known benefits for cardiovascular function, type II diabetes, and anti‐inflammation, recent …

Emerging perspective: role of increased ROS and redox imbalance in skin carcinogenesis

D Xian, R Lai, J Song, X Xiong… - Oxidative medicine and …, 2019 - Wiley Online Library
Strategies to battle malignant tumors have always been a dynamic research endeavour.
Although various vehicles (eg, chemotherapeutic therapy, radiotherapy, surgical resection …

Nrf2—A regulator of keratinocyte redox signaling

M Schäfer, S Werner - Free Radical Biology and Medicine, 2015 - Elsevier
The skin is frequently exposed to environmental challenges, such as UV irradiation, toxic
chemicals, and mechanical wounding. These insults cause an increase in the levels of …

Effect of ultraviolet radiation on the Nrf2 signaling pathway in skin cells

A Ryšavá, J Vostálová… - International Journal of …, 2021 - Taylor & Francis
Purpose Excessive exposure of skin to solar radiation is associated with greatly increased
production of reactive oxygen and nitrogen species (ROS, RNS) resulting in oxidative stress …

Natural xanthones and skin inflammatory diseases: Multitargeting mechanisms of action and potential application

NV Gunter, SS Teh, YM Lim, SH Mah - Frontiers in Pharmacology, 2020 - frontiersin.org
The pathogenesis of skin inflammatory diseases such as atopic dermatitis, acne, psoriasis,
and skin cancers generally involve the generation of oxidative stress and chronic …

NRF2 in dermatological disorders: Pharmacological activation for protection against cutaneous photodamage and photodermatosis

S Kahremany, L Hofmann, A Gruzman… - Free Radical Biology …, 2022 - Elsevier
The skin barrier and its endogenous protective mechanisms cope daily with exogenous
stressors, of which ultraviolet radiation (UVR) poses an imminent danger. Although the skin …

Poly-D, L-lactic acid filler increases extracellular matrix by modulating macrophages and adipose-derived stem cells in aged animal skin

S Oh, SB Seo, G Kim, S Batsukh, CH Park, KH Son… - Antioxidants, 2023 - mdpi.com
Poly-D, L-lactic acid (PDLLA) filler corrects soft tissue volume loss by increasing collagen
synthesis in the dermis; however, the mechanism is not fully understood. Adipose-derived …

Topical treatment with pterostilbene, a natural phytoalexin, effectively protects hairless mice against UVB radiation-induced skin damage and carcinogenesis

JA Sirerol, F Feddi, S Mena, ML Rodriguez… - Free Radical Biology …, 2015 - Elsevier
The aim of our study was to investigate in the SKH-1 hairless mouse model the effect of
pterostilbene (Pter), a natural dimethoxy analog of resveratrol (Resv), against …