Antimicrobial peptides: Promising alternatives in the post feeding antibiotic era

J Wang, X Dou, J Song, Y Lyu, X Zhu… - Medicinal research …, 2019 - Wiley Online Library
Antimicrobial peptides (AMPs), critical components of the innate immune system, are widely
distributed throughout the animal and plant kingdoms. They can protect against a broad …

Antimicrobial peptides and proteins: From nature's reservoir to the laboratory and beyond

T Sarkar, M Chetia, S Chatterjee - Frontiers in Chemistry, 2021 - frontiersin.org
Rapid rise of antimicrobial resistance against conventional antimicrobials, resurgence of
multidrug resistant microbes and the slowdown in the development of new classes of …

The antimicrobial peptide ZY4 combats multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii infection

J Mwangi, Y Yin, G Wang, M Yang… - Proceedings of the …, 2019 - National Acad Sciences
The emergence of carbapenem-resistant Acinetobacter baumannii and Pseudomonas
aeruginosa raises fears of untreatable infections and poses the greatest health threats …

Non-membrane permeabilizing modes of action of antimicrobial peptides on bacteria

M Scocchi, M Mardirossian, G Runti… - Current topics in …, 2016 - ingentaconnect.com
Antimicrobial peptides (AMPs) are a large class of innate immunity effectors with a
remarkable capacity to inactivate microorganisms. Their ability to kill bacteria by …

[HTML][HTML] Sequential release of milk protein–derived bioactive peptides in the jejunum in healthy humans

R Boutrou, C Gaudichon, D Dupont, J Jardin… - The American journal of …, 2013 - Elsevier
Background: The digestive hydrolysis of dietary proteins leads to the release of peptides in
the intestinal tract, where they may exert a variety of functions, but their characterization and …

Tryptophan-rich and proline-rich antimicrobial peptides

AK Mishra, J Choi, E Moon, KH Baek - Molecules, 2018 - mdpi.com
Due to the increasing emergence of drug-resistant pathogenic microorganisms, there is a
world-wide quest to develop new-generation antibiotics. Antimicrobial peptides (AMPs) are …

Peptides and peptidomimetics for antimicrobial drug design

B Mojsoska, H Jenssen - Pharmaceuticals, 2015 - mdpi.com
The purpose of this paper is to introduce and highlight a few classes of traditional
antimicrobial peptides with a focus on structure-activity relationship studies. After first …

Antimicrobial peptides as anti-infective agents in pre-post-antibiotic era?

T Rončević, J Puizina, A Tossi - International journal of molecular …, 2019 - mdpi.com
Resistance to antibiotics is one of the main current threats to human health and every year
multi-drug resistant bacteria are infecting millions of people worldwide, with many dying as a …

Proline-rich antimicrobial peptides: potential therapeutics against antibiotic-resistant bacteria

W Li, J Tailhades, NM O'Brien-Simpson, F Separovic… - Amino acids, 2014 - Springer
The increasing resistance of pathogens to antibiotics causes a huge clinical burden that
places great demands on academic researchers and the pharmaceutical industry for …

An overview of the potentialities of antimicrobial peptides derived from natural sources

I Dini, MG De Biasi, A Mancusi - Antibiotics, 2022 - mdpi.com
Antimicrobial peptides (AMPs) are constituents of the innate immune system in every kind of
living organism. They can act by disrupting the microbial membrane or without affecting …