TonB-dependent transport across the bacterial outer membrane

A Silale, B van den Berg - Annual Review of Microbiology, 2023 - annualreviews.org
TonB-dependent transporters (TBDTs) are present in all gram-negative bacteria and
mediate energy-dependent uptake of molecules that are too scarce or large to be taken up …

One-pot synthesis of bimetallic metal–organic frameworks (MOFs) as acid–base bifunctional catalysts for tandem reaction

Y Hu, J Zhang, H Huo, Z Wang, X Xu, Y Yang… - Catalysis Science & …, 2020 - pubs.rsc.org
Designing and preparing effective acid–base tandem catalysts is one of the research
hotspots at present because assembling antagonistic active sites in one catalyst is still a …

Structural Basis for Evasion of Nutritional Immunity by the Pathogenic Neisseriae

R Yadav, N Noinaj, N Ostan, T Moraes… - Frontiers in …, 2020 - frontiersin.org
The pathogenic Neisseria species are human-adapted pathogens that cause quite distinct
diseases. Neisseria gonorrhoeae causes the common sexually transmitted infection …

The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD

C Calmettes, C Ing, CM Buckwalter… - Nature …, 2015 - nature.com
Invading bacteria from the Neisseriaceae, Acinetobacteriaceae, Bordetellaceae and
Moraxellaceae families express the conserved outer-membrane zinc transporter zinc-uptake …

Profiling IgG and IgA antibody responses during vaccination and infection in a high-risk gonorrhoea population

L Stejskal, A Thistlethwaite… - Nature …, 2024 - nature.com
Abstract Development of a vaccine against gonorrhoea is a global priority, driven by the rise
in antibiotic resistance. Although Neisseria gonorrhoeae (Ng) infection does not induce …

The structure of the bacterial iron–catecholate transporter Fiu suggests that it imports substrates via a two-step mechanism

R Grinter, T Lithgow - Journal of Biological Chemistry, 2019 - ASBMB
The ferric iron uptake (Fiu) transporter from Escherichia coli functions in the transport of iron–
catecholate complexes across the bacterial outer membrane, providing the bacterium with …

[HTML][HTML] A novel meningococcal outer membrane vesicle vaccine with constitutive expression of FetA: A phase I clinical trial

L Marsay, C Dold, CA Green, CS Rollier, G Norheim… - Journal of infection, 2015 - Elsevier
Objectives Outer membrane vesicle (OMV) vaccines are used against outbreaks of capsular
group B Neisseria meningitidis (MenB) caused by strains expressing particular PorA outer …

Nickel import and export in the human pathogen Helicobacter pylori, perspectives from molecular modelling

G Camporesi, A Minzoni, L Morasso, S Ciurli… - Metallomics, 2021 - academic.oup.com
The uptake of essential metal ions and the ability to extrude them when their excess causes
toxicity are crucial processes for all living beings. Nickel is a virulence factor for several …

Structural and functional insights into iron acquisition from lactoferrin and transferrin in Gram-negative bacterial pathogens

C Chan, D Ng, ME Fraser, AB Schryvers - BioMetals, 2023 - Springer
Iron is an essential element for various lifeforms but is largely insoluble due to the
oxygenation of Earth's atmosphere and oceans during the Proterozoic era. Metazoans …

Distribution and diversity of the haemoglobin–haptoglobin iron-acquisition systems in pathogenic and non-pathogenic Neisseria

OB Harrison, JS Bennett, JP Derrick… - …, 2013 - microbiologyresearch.org
A new generation of vaccines containing multiple protein components that aim to provide
broad protection against serogroup B meningococci has been developed. One candidate …