Revisiting the Global Epidemiology of Cholera in Conjunction With the Genomics of Vibrio cholerae

T Ramamurthy, A Mutreja, FX Weill, B Das… - Frontiers in public …, 2019 - frontiersin.org
Toxigenic Vibrio cholerae is responsible for 1.4 to 4.3 million cases with about 21,000–
143,000 deaths per year. Dominance of O1 and O139 serogroups, classical and El tor …

Two defence systems eliminate plasmids from seventh pandemic Vibrio cholerae

M Jaskólska, DW Adams, M Blokesch - Nature, 2022 - nature.com
Horizontal gene transfer can trigger rapid shifts in bacterial evolution. Driven by a variety of
mobile genetic elements—in particular bacteriophages and plasmids—the ability to share …

The origin of the Haitian cholera outbreak strain

CS Chin, J Sorenson, JB Harris… - … England Journal of …, 2011 - Mass Medical Soc
Background Although cholera has been present in Latin America since 1991, it had not
been epidemic in Haiti for at least 100 years. Recently, however, there has been a severe …

Coordinated regulation of accessory genetic elements produces cyclic di-nucleotides for V. cholerae virulence

BW Davies, RW Bogard, TS Young, JJ Mekalanos - Cell, 2012 - cell.com
The function of the Vibrio 7 th pandemic island-1 (VSP-1) in cholera pathogenesis has
remained obscure. Utilizing chromatin immunoprecipitation sequencing and RNA …

Genomic diversity of 2010 Haitian cholera outbreak strains

NA Hasan, SY Choi, M Eppinger… - Proceedings of the …, 2012 - National Acad Sciences
The millions of deaths from cholera during the past 200 y, coupled with the morbidity and
mortality of cholera in Haiti since October 2010, are grim reminders that Vibrio cholerae, the …

Cholera Outbreaks in Nigeria Are Associated with Multidrug Resistant Atypical El Tor and Non-O1/Non-O139 Vibrio cholerae

MA Marin, CC Thompson, FS Freitas… - PLoS neglected …, 2013 - journals.plos.org
Background The current millennium has seen a steep rise in the number, size and case-
fatalities of cholera outbreaks in many African countries. Over 40,000 cases of cholera were …

The Vibrio cholerae Seventh Pandemic Islands act in tandem to defend against a circulating phage

BJ O'Hara, M Alam, WL Ng - PLoS genetics, 2022 - journals.plos.org
The current circulating pandemic El Tor biotype of Vibrio cholerae has persisted for over
sixty years and is characterized by its acquisition of two unique genomic islands called the …

Detection, Isolation, and Identification of Vibrio cholerae from the Environment

A Huq, BJ Haley, E Taviani, A Chen… - Current protocols in …, 2012 - Wiley Online Library
Recent molecular advances in microbiology have greatly improved the detection of bacterial
pathogens in the environment. These improvements and a downward trend in the cost of …

Environmental role of pathogenic traits in Vibrio cholerae

SN Sakib, G Reddi, S Almagro-Moreno - 2018 - Am Soc Microbiol
Vibrio cholerae is a natural inhabitant of aquatic ecosystems. Some strains of V. cholerae
can colonize human hosts and cause cholera, a profuse watery diarrhea. The major …

Genome Sequence of Hybrid Vibrio cholerae O1 MJ-1236, B-33, and CIRS101 and Comparative Genomics with V. cholerae

CJ Grim, NA Hasan, E Taviani, B Haley… - Journal of …, 2010 - Am Soc Microbiol
The genomes of V ibrio cholerae O1 Matlab variant MJ-1236, Mozambique O1 El Tor variant
B33, and altered O1 El Tor CIRS101 were sequenced. All three strains were found to belong …