Pathogenesis and control of the Chinese highly pathogenic porcine reproductive and respiratory syndrome virus

J Han, L Zhou, X Ge, X Guo, H Yang - Veterinary microbiology, 2017 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) has remained a major threat
to the worldwide swine industry ever since its first discovery in the early 1990s. Under the …

[HTML][HTML] Proteomics of SARS-CoV-2-infected host cells reveals therapy targets

D Bojkova, K Klann, B Koch, M Widera, D Krause… - Nature, 2020 - nature.com
A new coronavirus was recently discovered and named severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). Infection with SARS-CoV-2 in humans causes coronavirus …

The diverse roles and dynamic rearrangement of vimentin during viral infection

Y Zhang, Z Wen, X Shi, YJ Liu… - Journal of cell …, 2021 - journals.biologists.com
Epidemics caused by viral infections pose a significant global threat. Cytoskeletal vimentin is
a major intermediate filament (IF) protein, and is involved in numerous functions, including …

Cholesterol 25-hydroxylase inhibits porcine reproductive and respiratory syndrome virus replication through enzyme activity-dependent and-independent …

W Ke, L Fang, H Jing, R Tao, T Wang, Y Li… - Journal of …, 2017 - Am Soc Microbiol
ABSTRACT Cholesterol 25-hydroxylase (CH25H) has recently been identified as a host
restriction factor that exerts antiviral effects by catalyzing the production of 25 …

[HTML][HTML] Research progress in porcine reproductive and respiratory syndrome virus–host protein interactions

H Zhang, H Sha, L Qin, N Wang, W Kong, L Huang… - Animals, 2022 - mdpi.com
Simple Summary PRRSV–host protein interactions are of great significance in finding new
antiviral targets. We summarize the effects of all the PRRSV structural and nonstructural …

[HTML][HTML] SARS-CoV-2 infected host cell proteomics reveal potential therapy targets

D Bojkova, K Klann, B Koch, M Widera, D Krause… - 2020 - europepmc.org
A novel coronavirus was recently discovered and termed SARS-CoV-2. Human infection can
cause coronavirus disease 2019 (COVID-19), for which, at this point, over 80,000 cases …

A nanobody inhibiting porcine reproductive and respiratory syndrome virus replication via blocking self-interaction of viral nucleocapsid protein

H Duan, X Chen, Z Zhang, Z Zhang, Z Li… - Journal of …, 2024 - Am Soc Microbiol
Porcine reproductive and respiratory syndrome (PRRS) is a serious global pig industry
disease. Understanding the mechanism of viral replication and developing efficient antiviral …

Porcine reproductive and respiratory syndrome virus nsp1β stabilizes HIF-1α to enhance viral replication

Y Pang, Y Zhou, Y Wang, Z Sun, J Liu, C Li… - Microbiology …, 2022 - Am Soc Microbiol
Porcine reproductive and respiratory syndrome virus (PRRSV) is an Arterivirus that has
been devastating the swine industry worldwide since the late 1980s. Severe interstitial …

[HTML][HTML] Cellular vimentin regulates the infectivity of Newcastle disease virus through targeting of the HN protein

X Lu, K Liu, Y Chen, R Gao, Z Hu, J Hu, M Gu, S Hu… - Veterinary …, 2023 - Springer
The haemagglutinin-neuraminidase (HN) protein plays a crucial role in the infectivity and
virulence of Newcastle disease virus (NDV). In a previous study, the mutant HN protein was …

[HTML][HTML] The nucleocapsid proteins of mouse hepatitis virus and severe acute respiratory syndrome coronavirus share the same IFN-β antagonizing mechanism …

Z Ding, L Fang, S Yuan, L Zhao, X Wang, S Long… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Coronaviruses (CoVs) are a huge threat to both humans and animals and have evolved
elaborate mechanisms to antagonize interferons (IFNs). Nucleocapsid (N) protein is the …