Metabolic regulation of neurodifferentiation in the adult brain

C Maffezzini, J Calvo-Garrido, A Wredenberg… - Cellular and Molecular …, 2020 - Springer
Understanding the mechanisms behind neurodifferentiation in adults will be an important
milestone in our quest to identify treatment strategies for cognitive disorders observed during …

Targeting mitochondrial metabolism in neuroinflammation: towards a therapy for progressive multiple sclerosis

L Peruzzotti-Jametti, S Pluchino - Trends in molecular medicine, 2018 - cell.com
The lack of effective treatment options for chronic neurological conditions, such as multiple
sclerosis (MS), highlights the need to re-evaluate disease pathophysiology in the process of …

SETBP1 accumulation induces P53 inhibition and genotoxic stress in neural progenitors underlying neurodegeneration in Schinzel-Giedion syndrome

F Banfi, A Rubio, M Zaghi, L Massimino… - Nature …, 2021 - nature.com
The investigation of genetic forms of juvenile neurodegeneration could shed light on the
causative mechanisms of neuronal loss. Schinzel-Giedion syndrome (SGS) is a fatal …

Modulation of hippocampal neural plasticity by glucose‐related signaling

M Mainardi, S Fusco, C Grassi - Neural plasticity, 2015 - Wiley Online Library
Hormones and peptides involved in glucose homeostasis are emerging as important
modulators of neural plasticity. In this regard, increasing evidence shows that molecules …

Three-dimensional graphene enhances neural stem cell proliferation through metabolic regulation

Q Fang, Y Zhang, X Chen, H Li, L Cheng… - … in Bioengineering and …, 2020 - frontiersin.org
Graphene consists of two-dimensional sp2-bonded carbon sheets, a single or a few layers
thick, which has attracted considerable interest in recent years due to its good conductivity …

[HTML][HTML] Folic acid supplementation improves seed germination, seedling growth and cadmium uptake in a mining ecotype of Solanum nigrum L.

ZA Sahito, A Zehra, S Yu, S Chen, MAR Arif… - … Technology & Innovation, 2024 - Elsevier
Cadmium (Cd) contamination poses a significant threat to global agricultural production and
hyperaccumulating plant species, such as Solanum nigrum (L.), face challenges in …

Glycosphingolipid metabolic reprogramming drives neural differentiation

D Russo, F Della Ragione, R Rizzo, E Sugiyama… - The EMBO …, 2018 - embopress.org
Neural development is accomplished by differentiation events leading to metabolic
reprogramming. Glycosphingolipid metabolism is reprogrammed during neural development …

Blood-brain barrier-supported neurogenesis in healthy and diseased brain

EA Pozhilenkova, OL Lopatina, YK Komleva… - Reviews in the …, 2017 - degruyter.com
Adult neurogenesis is one of the most important mechanisms contributing to brain
development, learning, and memory. Alterations in neurogenesis underlie a wide spectrum …

TIGAR promotes neural stem cell differentiation through acetyl-CoA-mediated histone acetylation

W Zhou, T Zhao, J Du, G Ji, X Li, S Ji, W Tian… - Cell death & …, 2019 - nature.com
Cellular metabolism plays a crucial role in controlling the proliferation, differentiation, and
quiescence of neural stem cells (NSCs). The metabolic transition from aerobic glycolysis to …

Scopolin obtained from Smilax china L. against hepatocellular carcinoma by inhibiting glycolysis: A network pharmacology and experimental study

C Wang, Q Zhou, ST Wu - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Smilax china L. is a well-known traditional medicinal plant.
In China, it is a common anti-cancer drug that has been inherited for thousands of years …