In recent years, several key advances in the management of locally advanced rectal cancer
have been made, including the implementation of total mesorectal excision as the standard …

Colorectal cancer (CRC) continues to be a global health concern, necessitating further
research into its complex biology and innovative treatment approaches. The etiology …

CSCO guidelines for colorectal cancer version 2023: Updates and insights - PMC Back to Top
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Rectal adenocarcinoma constitutes about one-third of all colorectal adenocarcinoma cases.
Rectal MRI has become mandatory for evaluation of patients newly diagnosed with rectal …

Background Accurately assessing the risk of recurrence in patients with locally advanced
rectal cancer (LARC) before treatment is important for the development of treatment …

The classification of extramural vascular invasion status using baseline magnetic resonance
imaging in rectal cancer has gained significant attention as it is an important prognostic …

Correct tumour restaging is pivotal for identifying the most personalised surgical treatment
for patients with locally advanced rectal cancer undergoing neoadjuvant therapy, and works …

Over the last few years, radiation therapy (RT) techniques have evolved very rapidly, with
the aim of conforming high-dose volume tightly to a target. Although to date CT is still …

Total neoadjuvant treatment (TNT) for rectal cancer is becoming an accepted treatment
paradigm and is changing the landscape of this disease, wherein up to 50% of patients who …

Rectal cancer (RC) is the third most frequently diagnosed cancer worldwide, and the status
of its circumferential resection margin (CRM) is of paramount significance for treatment …