Towards advances in medicinal plant antimicrobial activity: A review study on challenges and future perspectives

N Vaou, E Stavropoulou, C Voidarou, C Tsigalou… - Microorganisms, 2021 - mdpi.com
The increasing incidence of drug-resistant pathogens raises an urgent need to identify and
isolate new bioactive compounds from medicinal plants using standardized modern …

Synergy and antagonism in natural product extracts: when 1+ 1 does not equal 2

LK Caesar, NB Cech - Natural product reports, 2019 - pubs.rsc.org
Covering: 2000 to 2019 According to a 2012 survey from the Centers for Disease Control
and Prevention, approximately 18% of the US population uses natural products (including …

Cannabis sativa: The Plant of the Thousand and One Molecules

CM Andre, JF Hausman, G Guerriero - Frontiers in plant science, 2016 - frontiersin.org
Cannabis sativa L. is an important herbaceous species originating from Central Asia, which
has been used in folk medicine and as a source of textile fiber since the dawn of times. This …

Interactions between medical plant-derived bioactive compounds: focus on antimicrobial combination effects

N Vaou, E Stavropoulou, C Voidarou, Z Tsakris… - Antibiotics, 2022 - mdpi.com
It is accepted that the medicinal use of complex mixtures of plant-derived bioactive
compounds is more effective than purified bioactive compounds due to beneficial …

[HTML][HTML] Antibacterial mechanisms of cinnamon and its constituents: A review

NG Vasconcelos, J Croda, S Simionatto - Microbial pathogenesis, 2018 - Elsevier
Background In the current healthcare environment, an alarming rise in multi-drug resistant
bacterial infections has led to a global health threat. The lack of new antibiotics has created …

Therapeutics Role of Azadirachta indica (Neem) and Their Active Constituents in Diseases Prevention and Treatment

MA Alzohairy - Evidence‐Based Complementary and …, 2016 - Wiley Online Library
Neem (Azadirachta indica) is a member of the Meliaceae family and its role as health‐
promoting effect is attributed because it is rich source of antioxidant. It has been widely used …

From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy

T Efferth - Seminars in cancer biology, 2017 - Elsevier
Artemisia annua L. is used throughout Asia and Africa as tea and press juice to treat malaria
and related symptomes (fever, chills). Its active ingredient, artemisinin (ARS), has been …

The immunosuppressive activity of artemisinin‐type drugs towards inflammatory and autoimmune diseases

T Efferth, F Oesch - Medicinal research reviews, 2021 - Wiley Online Library
The sesquiterpene lactone artemisinin from Artemisia annua L. is well established for
malaria therapy, but its bioactivity spectrum is much broader. In this review, we give a …

Identification of novel compounds against three targets of SARS CoV-2 coronavirus by combined virtual screening and supervised machine learning

O Kadioglu, M Saeed, HJ Greten, T Efferth - Computers in biology and …, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a major threat worldwide due to its fast
spreading. As yet, there are no established drugs available. Speeding up drug discovery is …

African herbal medicines: Adverse effects and cytotoxic potentials with different therapeutic applications

K Okaiyeto, OO Oguntibeju - … journal of environmental research and public …, 2021 - mdpi.com
The African continent is naturally endowed with various plant species with nutritional and
medicinal benefits. About 80% of the people in developing countries rely on folk medicines …