Disrupted protein folding or decreased protein stability can lead to the accumulation of
(partially) un‐or misfolded proteins, which ultimately cause the formation of protein …

Stress granules (SGs) are phase-separated, membraneless, cytoplasmic ribonucleoprotein
(RNP) assemblies whose primary function is to promote cell survival by condensing …

The accumulation of amyloid fibrils is characteristic of neurodegenerative diseases such as
Alzheimer's disease (AD) and Parkinson's disease. Detecting these fibrils with fluorescent or …

Alzheimer's disease (AD) is a neurodegenerative disorder with neuronal and synaptic
losses due to the accumulation of toxic amyloid β (Αβ) peptide oligomers, plaques, and …

Similar to neurodegenerative diseases, the concept that tumors are prion like diseases has
been proposed in recent years. p53, the most well-known tumor suppressor, has been …

The abundance of intrinsic disorder in the protein realm and its role in a variety of
physiological and pathological cellular events have strengthened the interest of the scientific …

Amyloid transthyretin (ATTR) amyloidosis is characterized by the abnormal accumulation of
ATTR fibrils in multiple organs. However, the structure of ATTR fibrils from the eye is poorly …

Protein misfolding and aggregation have attracted immense research interests due to their
connection with an array of degenerative diseases including neurodegenerative disorders …

Liquid–liquid phase separation (LLPS) is an emerging phenomenon in cell physiology and
diseases. The weak multivalent interaction prerequisite for LLPS is believed to be facilitated …

Amyloid formation continues to be a widely studied area due to its association with
numerous diseases, such as Alzheimer's and Parkinson's diseases. Despite a large body of …