Surgical margins in head and neck cancer: Intra-and postoperative considerations

KT Robbins, A Triantafyllou, C Suárez, F López… - Auris Nasus …, 2019 - Elsevier
Objective To provide a perspective on the significance of recent reports for optimizing cancer
free surgical margins that have challenged standard practices. Methods We conducted a …

Margin analysis in head and neck cancer: state of the art and future directions

MM Li, SV Puram, DA Silverman, MO Old… - Annals of surgical …, 2019 - Springer
Background The status of surgical margins is the most important prognosticator for patients
undergoing surgical resection of head and neck squamous cell carcinoma (HNSCC) …

[HTML][HTML] Methylation status of homeobox genes in common human cancers

MFSD Rodrigues, CM Esteves, FCA Xavier, FD Nunes - Genomics, 2016 - Elsevier
Approximately 300 homeobox loci were identified in the euchromatic regions of the human
genome, of which 235 are probable functional genes and 65 are likely pseudogenes. Many …

Discovery and development of differentially methylated regions in human papillomavirus‐related oropharyngeal squamous cell carcinoma

S Ren, D Gaykalova, J Wang, T Guo… - … journal of cancer, 2018 - Wiley Online Library
Human papillomavirus (HPV)‐related oropharyngeal squamous cell carcinoma (OPSCC)
exhibits a different composition of epigenetic alterations. In this study, we identified …

The role of tumor DNA as a diagnostic tool for head and neck squamous cell carcinoma

JYK Chan, G Zhen, N Agrawal - Seminars in Cancer Biology, 2019 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) represents the most common type of
head and neck cancer worldwide. However, despite advances in cancer care globally there …

Head and neck cancers are not alike when tarred with the same brush: An epigenetic perspective from the cancerization field to prognosis

D Camuzi, TA Simão, F Dias, LF Ribeiro Pinto… - Cancers, 2021 - mdpi.com
Simple Summary Squamous cell carcinomas affect different head and neck subsites and,
although these tumors arise from the same epithelial lining and share risk factors, they differ …

Fluid biomarkers in HPV and non-HPV related oropharyngeal carcinomas: from diagnosis and monitoring to prognostication—a systematic Review

SC Lee, KKC Leung, ACY Chung, ESY Wong… - International Journal of …, 2022 - mdpi.com
Biomarkers are crucial in oncology, from detection and monitoring to guiding management
and predicting treatment outcomes. Histological assessment of tissue biopsies is currently …

DNA methylation markers from negative surgical margins can predict recurrence of oral squamous cell carcinoma

BP Sorroche, FR Talukdar, SCS Lima, ME Melendez… - Cancers, 2021 - mdpi.com
Simple Summary Up to 30% of oral cavity cancer patients with pathologically negative
surgical margins usually exhibit tumor recurrence. Early molecular alterations in the tumor …

Diagnostic value of the methylation of multiple gene promoters in serum in hepatitis B virus‐related hepatocellular carcinoma

X Dong, Q Hou, Y Chen, X Wang - Disease Markers, 2017 - Wiley Online Library
This study sought to evaluate the diagnostic value of the methylation of multiple gene
promoters in serum in hepatitis B virus‐(HBV‐) related hepatocellular carcinoma (HCC). A …

Margin analysis: squamous cell carcinoma of the oral cavity

M Shapiro, A Salama - Oral and Maxillofacial Surgery …, 2017 - oralmaxsurgery.theclinics.com
Oral squamous cell carcinoma (OSCC) is the most common oral malignancy, accounting for
more than 90% of oral cancers. In the United States, OSCC represents nearly 4% of all …