Mammalian prion or PrPSc is a proteinaceous infectious agent that consists of a misfolded,
self-replicating state of a sialoglycoprotein called the prion protein, or PrPC. Sialylation of …

The cellular prion protein PrPC was initially discovered as the normal counterpart of the
pathological scrapie prion protein PrPSc, the main component of the infectious agent of …

Prion protein (PrP C) is a cell surface glycoprotein whose misfolding is responsible for prion
diseases. Although its physiological role is not completely defined, several lines of evidence …

Prion protein (PrP C) is implicated in the pathogenesis of prion disorders, but its normal
function is unclear. We demonstrate that PrP C is a ferrireductase (FR), and its absence …

The possibilities for diagnosing prion diseases have shifted significantly over the last 10
years. The RT-QuIC assay option has been added for neuropsychiatric symptoms …

Prion protein (PrPC), is a glycoprotein that is expressed on the cell surface. The current
study examines the role of PrPC in early human embryogenesis using human embryonic …

The PrPC protein, which is especially present in the cellular membrane of nervous system
cells, has been extensively studied for its controversial antioxidant activity. In this study, we …

Prion diseases are fatal neurodegenerative processes caused by the accumulation of the
pathological prion protein, PrPSc. While pathological lesions are limited to the central …

Although initially disregarded compared to prion pathogenesis, the functions exerted by the
cellular prion protein PrP C have gained much interest over the past two decades. Research …

Prion protein, PrPC, is a glycoprotein that is expressed on the cell surface beginning with the
early stages of embryonic stem cell differentiation. Previously, we showed that ectopic …