Anticancer drugs: recent strategies to improve stability profile, pharmacokinetic and pharmacodynamic properties
G Ioele, M Chieffallo, MA Occhiuzzi, M De Luca… - Molecules, 2022 - mdpi.com
In past decades, anticancer research has led to remarkable results despite many of the
approved drugs still being characterized by high systemic toxicity mainly due to the lack of …
approved drugs still being characterized by high systemic toxicity mainly due to the lack of …
[HTML][HTML] Liposome-polymer complex for drug delivery system and vaccine stabilization
Liposomes have been used extensively as micro-and nanocarriers for hydrophobic or
hydrophilic molecules. However, conventional liposomes are biodegradable and quickly …
hydrophilic molecules. However, conventional liposomes are biodegradable and quickly …
Novel findings for quercetin encapsulation and preservation with cyclodextrins, liposomes, and drug-in-cyclodextrin-in-liposomes
J Azzi, A Jraij, L Auezova, S Fourmentin… - Food …, 2018 - Elsevier
The low solubility, poor bioavailability, and low chemical stability of quercetin (Quer) are the
main drawbacks that limit its use as a food nutraceutical. In this study, the encapsulation in …
main drawbacks that limit its use as a food nutraceutical. In this study, the encapsulation in …
1, 4-Dihydropyridine antihypertensive drugs: Recent advances in photostabilization strategies
The 1, 4-dihydropyridine (DHP) drugs are nowadays the most used drugs in the treatment of
hypertension. However, all the structures in this series present a significant sensitivity to …
hypertension. However, all the structures in this series present a significant sensitivity to …
First evaluation of drug-in-cyclodextrin-in-liposomes as an encapsulating system for nerolidol
Nerolidol, a naturally occurring sesquiterpene with antimicrobial activities, is a promising
candidate as a natural alternative for synthetic preservatives in food. However, its …
candidate as a natural alternative for synthetic preservatives in food. However, its …
Photosensitive drugs: A review on their photoprotection by liposomes and cyclodextrins
Nowadays, an exciting challenge in the drug chemistry and technology research is
represented by the development of methods aimed to protect molecular integrity and …
represented by the development of methods aimed to protect molecular integrity and …
Complex systems that incorporate cyclodextrins to get materials for some specific applications
MA Fernández, OF Silva, RV Vico, RH de Rossi - Carbohydrate research, 2019 - Elsevier
Cyclodextrins (CDs) are a family of biodegradable cyclic hydrocarbons composed of α-(1, 4)
linked glucopyranose subunits, the more common containing 6, 7 or 8 glucose units are …
linked glucopyranose subunits, the more common containing 6, 7 or 8 glucose units are …
Photostability issues in pharmaceutical dosage forms and photostabilization
Photodegradation is one of the major pathways of the degradation of drugs. Some
therapeutic agents and excipients are highly sensitive to light and undergo significant …
therapeutic agents and excipients are highly sensitive to light and undergo significant …
Photodegradation of anti-inflammatory drugs: Stability tests and lipid nanocarriers for their photoprotection
The present paper provides an updated overview of the methodologies applied in
photodegradation studies of non-steroidal anti-inflammatory drugs. Photostability tests …
photodegradation studies of non-steroidal anti-inflammatory drugs. Photostability tests …
Nanoplatform Based Intranasal Vaccines: Current Progress and Clinical Challenges
Z Bai, D Wan, T Lan, W Hong, H Dong, Y Wei, X Wei - ACS nano, 2024 - ACS Publications
Multiple vaccine platforms have been employed to develop the nasal SARS-CoV-2 vaccines
in preclinical studies, and the dominating pipelines are viral vectored as protein-based …
in preclinical studies, and the dominating pipelines are viral vectored as protein-based …