[HTML][HTML] Modern isolation and separation techniques for extracellular vesicles

T Liangsupree, E Multia, ML Riekkola - Journal of Chromatography A, 2021 - Elsevier
Extracellular vesicles (EVs) are heterogenous membrane-bound vesicles released from
various origins. EVs play a crucial role in cellular communication and mediate several …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Label-free isolation of exosomes using microfluidic technologies

S Hassanpour Tamrin, A Sanati Nezhad, A Sen - ACS nano, 2021 - ACS Publications
Exosomes are cell-derived structures packaged with lipids, proteins, and nucleic acids. They
exist in diverse bodily fluids and are involved in physiological and pathological processes …

[HTML][HTML] Glycosylation of cancer extracellular vesicles: capture strategies, functional roles and potential clinical applications

ÁM Martins, CC Ramos, D Freitas, CA Reis - Cells, 2021 - mdpi.com
Glycans are major constituents of extracellular vesicles (EVs). Alterations in the
glycosylation pathway are a common feature of cancer cells, which gives rise to de novo or …

[HTML][HTML] Targeting ADAM10 in cancer and autoimmunity

TM Smith Jr, A Tharakan, RK Martin - Frontiers in immunology, 2020 - frontiersin.org
Generating inhibitors for AD isintegrin A nd M etalloproteinase 10 (ADAM10), a zinc-
dependent protease, was heavily invested in by the pharmaceutical industry starting over 20 …

[HTML][HTML] Identification of distinct N-glycosylation patterns on extracellular vesicles from small-cell and non–small-cell lung cancer cells

K Kondo, Y Harada, M Nakano, T Suzuki… - Journal of Biological …, 2022 - ASBMB
Asparagine-linked glycosylation (N-glycosylation) of proteins in the cancer secretome has
been gaining increasing attention as a potential biomarker for cancer detection and …

Comprehensive review of MS‐based studies on N‐glycoproteome and N‐glycome of extracellular vesicles

Y Li, J Wang, W Chen, H Lu, Y Zhang - Proteomics, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are lipid bilayer‐enclosed particles that can be released by all
type of cells. Whereas, as one of the most common post‐translational modifications …

[HTML][HTML] Lectins as potential tools for cancer biomarker discovery from extracellular vesicles

MK Islam, M Khan, K Gidwani, KW Witwer… - Biomarker …, 2023 - Springer
Extracellular vesicles (EVs) have considerable potential as diagnostic, prognostic, and
therapeutic agents, in large part because molecular patterns on the EV surface betray the …

[HTML][HTML] Structure and function of glycosphingolipids on small extracellular vesicles

X He, F Guan, L Lei - Glycoconjugate Journal, 2022 - Springer
Extracellular vesicles (EVs) are membrane-delineated particles secreted by most types of
cells under both normal and pathophysiological conditions. EVs are believed to mediate …

[HTML][HTML] Fucosylated exosomal miRNAs as promising biomarkers for the diagnosis of early lung adenocarcinoma

X Chen, L Yu, K Hao, X Yin, M Tu, L Cai… - Frontiers in …, 2022 - frontiersin.org
Background Considering the absence of apparent symptoms at the early stage, most
patients with lung adenocarcinoma (LUAD) present at an advanced stage, leading to a …