[HTML][HTML] Central serous chorioretinopathy: towards an evidence-based treatment guideline

TJ Van Rijssen, EH Van Dijk, S Yzer… - Progress in retinal and …, 2019 - Elsevier
Central serous chorioretinopathy (CSC) is a common cause of central vision loss, primarily
affecting men 20–60 years of age. To date, no consensus has been reached regarding the …

Pachychoroid disease

CMG Cheung, WK Lee, H Koizumi, K Dansingani… - Eye, 2019 - nature.com
Pachychoroid is a relatively novel concept describing a phenotype characterized by
attenuation of the choriocapillaris overlying dilated choroidal veins, and associated with …

[HTML][HTML] Mechanisms of macular edema: beyond the surface

A Daruich, A Matet, A Moulin, L Kowalczuk… - Progress in retinal and …, 2018 - Elsevier
Macular edema consists of intra-or subretinal fluid accumulation in the macular region. It
occurs during the course of numerous retinal disorders and can cause severe impairment of …

[HTML][HTML] Central serous chorioretinopathy: recent findings and new physiopathology hypothesis

A Daruich, A Matet, A Dirani, E Bousquet… - Progress in retinal and …, 2015 - Elsevier
Central serous chorioretinopathy (CSCR) is a major cause of vision threat among middle-
aged male individuals. Multimodal imaging led to the description of a wide range of CSCR …

Central serous chorioretinopathy: an update on risk factors, pathophysiology and imaging modalities

R Kaye, S Chandra, J Sheth, CJF Boon… - Progress in Retinal and …, 2020 - Elsevier
Central serous chorioretinopathy (CSC) is a common form of vision loss, typically seen in
working-age men. The pathophysiology behind CSC still eludes us, however significant …

Eplerenone for chronic central serous chorioretinopathy in patients with active, previously untreated disease for more than 4 months (VICI): a randomised, double …

A Lotery, S Sivaprasad, A O'Connell, RA Harris… - The Lancet, 2020 - thelancet.com
Background In chronic central serous chorioretinopathy (CSCR), fluid accumulates in the
subretinal space. CSCR is a common visually disabling condition that develops in …

The renin-angiotensin-aldosterone system and its therapeutic targets

KMM Colafella, DM Bovée, AHJ Danser - Experimental eye research, 2019 - Elsevier
The renin-angiotensin-aldosterone system (RAAS) plays a pivotal role in the regulation of
blood pressure and body fluid homeostasis and is a mainstay for the treatment of …

Emerging roles of the mineralocorticoid receptor in pathology: toward new paradigms in clinical pharmacology

F Jaisser, N Farman, RM Touyz - Pharmacological reviews, 2016 - Elsevier
The mineralocorticoid receptor (MR) and its ligand aldosterone are the principal modulators
of hormone-regulated renal sodium reabsorption. In addition to the kidney, there are several …

60 years of neuroendocrinology: redefining neuroendocrinology: stress, sex and cognitive and emotional regulation

BS McEwen, JD Gray, C Nasca - Journal of endocrinology, 2015 - joe.bioscientifica.com
The discovery of steroid hormone receptors in brain regions that mediate every aspect of
brain function has broadened the definition of 'neuroendocrinology'to include the reciprocal …

Mineralocorticoid receptor antagonism in the treatment of chronic central serous chorioretinopathy: a pilot study

E Bousquet, T Beydoun, M Zhao, L Hassan, O Offret… - Retina, 2013 - journals.lww.com
Purpose: Based on experimental data showing that central serous chorioretinopathy could
result from overactivation of mineralocorticoid receptor pathway in choroid vessels, the …