The overall lifetime risk of heart failure (HF) is similar between men and women, however,
there are marked sex differences in the landscape of this condition that are both important …

Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …

Heart failure with preserved ejection fraction (HFpEF) represents a highly heterogeneous
clinical syndrome affected in its development and progression by many comorbidities. The …

Background: Heart failure (HF) with preserved ejection fraction (HFpEF) is a heterogeneous
syndrome. Phenotyping patients into pathophysiologically homogeneous groups may …

Research in the last decade has substantially advanced our understanding of the
pathophysiology of heart failure with preserved ejection fraction (HFpEF). However …

Objectives This study determined the impact of excess epicardial adipose tissue (EAT) in
patients with the obese phenotype of heart failure with preserved ejection fraction (HFpEF) …

Heart failure (HF) continues to be a major contributor of morbidity and mortality for men and
women alike, yet how the predisposition for, course and management of HF differ between …

Obesity increases the risks of developing cardiovascular and metabolic diseases and
degrades quality of life, ultimately increasing the risk of death. However, not all forms of …

Aims Central obesity is a major risk factor for heart failure with preserved ejection fraction
(HFpEF), particularly in women, but the mechanisms remain unclear. We hypothesized that …

Accumulating evidence points to the existence of an inflammatory‐metabolic phenotype of
heart failure with a preserved ejection fraction (HFpEF), which is characterized by …