Association between obesity, inflammation and insulin resistance: Insights into signaling pathways and therapeutic interventions

SS Garg, K Kushwaha, R Dubey, J Gupta - Diabetes research and clinical …, 2023 - Elsevier
Obesity, a metabolic disorder, is becoming a worldwide epidemic that predominantly
increases the risk for various diseases including metabolic inflammation, insulin resistance …

A comprehensive review on therapeutic perspectives of phytosterols in insulin resistance: a mechanistic approach

M Prasad, S Jayaraman, MA Eladl, M El-Sherbiny… - Molecules, 2022 - mdpi.com
Natural products in the form of functional foods have become increasingly popular due to
their protective effects against life-threatening diseases, low risk of adverse effects …

Impact of glyphosate on the development of insulin resistance in experimental diabetic rats: role of NFκB signalling pathways

M Prasad, MK Gatasheh, MA Alshuniaber… - Antioxidants, 2022 - mdpi.com
Glyphosate, an endocrine disruptor, has an adverse impact on human health through food
and also has the potential to produce reactive oxygen species (ROS), which can lead to …

Research progress on the mechanism between polycystic ovary syndrome and abnormal endometrium

Z Xue, J Li, J Feng, H Han, J Zhao, J Zhang… - Frontiers in …, 2021 - frontiersin.org
As a highly dynamic tissue, the endometrium is periodically shed in response to the
secretion of estrogen and progesterone. After menarche, the endometrium of healthy women …

[Retracted] Beta‐Sitosterol Facilitates GLUT4 Vesicle Fusion on the Plasma Membrane via the Activation of Rab/IRAP/Munc 18 Signaling Pathways in Diabetic …

JJ Pei, M Prasad, G Mohamed Helal… - Bioinorganic …, 2022 - Wiley Online Library
Nutritional overload in the form of high‐fat and nonglycolysis sugar intake contributes
towards the accelerated creation of reactive oxygen species (ROS), hyperglycemia, and …

Computational simulations of identified marine-derived natural bioactive compounds as potential inhibitors of oral cancer

PM Natarajan, VR Umapathy, A Murali… - Future Science …, 2022 - Taylor & Francis
Oral squamous cell carcinoma is characterized by the upregulation of RAC-alpha
serine/threonine-protein kinase (Akt1) and RAC-beta serine/threonine-protein kinase (Akt2) …

Biosynthesis of silver nanoparticles (AgNPs) using ethanolic extract of Nigella sativa (L.) seeds promotes wound healing via PDGF and VEGF signalling pathways …

CP Palanisamy, S Poompradub… - Biocatalysis and …, 2023 - Elsevier
In this study biosynthesis approach was employed to synthesis silver nanoparticles (AgNPs)
using Nigella sativa (N. sativa) seed extract (NSSE) as reducing and stabilizing agent for …

A network pharmacology and molecular docking approach to reveal the mechanism of Chaihu Anxin Capsule in depression

L Yang, Y Zhao, R Qu, Y Fu, C Zhou… - Frontiers in Endocrinology, 2023 - frontiersin.org
Introduction As one of the most frequently diagnosed mental disorders, depression is
expected to become the most common disease worldwide by 2030. Previous studies have …

Underlying biochemical effects of intermittent fasting, exercise and honey on streptozotocin-induced liver damage in rats

E Agbonifo-Chijiokwu, KE Nwangwa… - Journal of Diabetes & …, 2023 - Springer
Purpose Derangements of liver transcriptional factors and enzymes have important
implications in diabetes-induced related complications. Hence, this study which consists of …

Molecular mechanism of Yi-Qi-Yang-Yin-Ye against obesity in rats using network pharmacology, molecular docking, and molecular dynamics simulations

F Sun, J Liu, J Xu, A Tariq, Y Wu, L Li - Arabian Journal of Chemistry, 2024 - Elsevier
The increasing prevalence of obesity globally, which as well as affecting people's daily lives
and increasing the risk of obesity complications, also threatens the health of animal …