The human body is host to large numbers of bacteriophages (phages)–a diverse group of
bacterial viruses that infect bacteria. Phage were previously regarded as bystanders that …

Conspectus In vitro-transcribed RNAs are emerging as new biologics for therapeutic
innovation, as exemplified by their application recently in SARS-CoV-2 vaccinations. RNAs …

The human body is colonized by a diverse collective of microorganisms, including bacteria,
fungi, protozoa and viruses. The smallest entity of this microbial conglomerate are the …

Messenger RNA based therapeutics have the potential to cause a big revolution in medicine
as they can facilitate personalized medicines and allow patients to produce their own …

Bacteriophages or phages, being the most abundant entities on earth, represent a potential
solution to a diverse range of problems. Phages are successful antibacterial agents whose …

Interferon (IFN)-γ is the uppermost cytokine implicated in anti-tumor immunity. With its
cytostatic, pro-apoptotic and immune-provoking effects, IFN-γ plays a central role in the …

The characteristic feature of healthy living organisms is the preservation of homeostasis.
Compelling evidence highlight that the DNA damage response and repair (DDR/R) and …

Obesity is associated with increased cancer rates and higher susceptibility to infections. The
adipose tissue of obese individuals is inflammatory and may negatively impact on innate …

Mitochondria, traditionally recognized as cellular'powerhouses' due to their pivotal role in
energy production, have emerged as multifunctional organelles at the intersection of …

Remarkable progress in bioengineering over the past two decades has enabled the
formulation of fundamental design principles for a variety of medical and non-medical …