Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics

A Carnicer-Lombarte, ST Chen… - … in Bioengineering and …, 2021 - frontiersin.org
The implantation of any foreign material into the body leads to the development of an
inflammatory and fibrotic process—the foreign body reaction (FBR). Upon implantation into a …

A review for the peripheral nerve interface designer

CE Larson, E Meng - Journal of neuroscience methods, 2020 - Elsevier
Informational density and relative accessibility of the peripheral nervous system make it an
attractive site for therapeutic intervention. Electrode-based electrophysiological interfaces …

Nanoporous graphene-based thin-film microelectrodes for in vivo high-resolution neural recording and stimulation

D Viana, ST Walston, E Masvidal-Codina, X Illa… - Nature …, 2024 - nature.com
One of the critical factors determining the performance of neural interfaces is the electrode
material used to establish electrical communication with the neural tissue, which needs to …

Multifaceted understanding of human nerve implants to design optimized electrodes for bioelectronics

G Valle, G Aiello, F Ciotti, P Cvancara, T Martinovic… - Biomaterials, 2022 - Elsevier
Bioelectronic medicine is a promising venue for treatment of disabilities using implantable
neural interfaces. Peripheral neurostimulation of residual nerves recently enabled multiple …

Flexible Neural Interface From Non‐Transient Silk Fibroin With Outstanding Conformality, Biocompatibility, and Bioelectric Conductivity

Z Hu, Y Liang, S Fan, Q Niu, J Geng… - Advanced …, 2024 - Wiley Online Library
Silk fibroin (SF) with good biocompatibility can enable an efficient and safe implementation
of neural interfaces. However, it has been difficult to achieve a robust integration of …

Systematic analysis of wavelet denoising methods for neural signal processing

G Baldazzi, G Solinas, J Del Valle… - Journal of Neural …, 2020 - iopscience.iop.org
Objective. Among the different approaches for denoising neural signals, wavelet-based
methods are widely used due to their ability to reduce in-band noise. All wavelet denoising …

Interfaces with the peripheral nervous system for the control of a neuroprosthetic limb: a review

KA Yildiz, AY Shin, KR Kaufman - Journal of neuroengineering and …, 2020 - Springer
The field of prosthetics has been evolving and advancing over the past decade, as patients
with missing extremities are expecting to control their prostheses in as normal a way as …

Upper limb prostheses: bridging the sensory gap

AD Roche, ZK Bailey, M Gonzalez… - Journal of Hand …, 2023 - journals.sagepub.com
Replacing human hand function with prostheses goes far beyond only recreating muscle
movement with feedforward motor control. Natural sensory feedback is pivotal for fine …

Biomedical and tissue engineering strategies to control foreign body reaction to invasive neural electrodes

M Gori, G Vadalà, SM Giannitelli, V Denaro… - … in Bioengineering and …, 2021 - frontiersin.org
Neural-interfaced prostheses aim to restore sensorimotor limb functions in amputees. They
rely on bidirectional neural interfaces, which represent the communication bridge between …

Neural signal recording and processing in somatic neuroprosthetic applications. A review

S Raspopovic, A Cimolato, A Panarese… - Journal of neuroscience …, 2020 - Elsevier
Neurointerfaces have acquired major relevance as both rehabilitative and therapeutic tools
for patients with spinal cord injury, limb amputations and other neural disorders …