The study reported here aimed to develop and optimize the S-SNEDDS tablet of bosentan
(BOS) and to investigate its pharmacokinetic and biodistribution properties. The BOS-loaded …

The lipid‐based drug delivery system (LBDDS) is a well‐established technique that is
anticipated to bring about comprehensive transformations in the pharmaceutical field …

The intestine is essential for the modulation of nutrient absorption and the removal of waste.
Gut pathologies, such as cancer, inflammatory bowel diseases (IBD), irritable bowel …

The aim of this study is to demonstrate a method for improving the solubility and relative
bioavailability of artemisinin using a self-emulsifying drug delivery system (SEDDS). The self …

Background The aim of the present study is to increase the solubility of dihydroartemisinin
(DHA) using the self-emulsifying drug delivery system (SEDDS). Methods We first conducted …

Aim: To evaluate the feasibility of using dipotassium glycyrrhizinate (DG) as a nanocarrier-
loading fisetin (FIT) with strengthened treatment efficacies against liver injury induced by …

Introduction We previously identified niclosamide as a promising repurposed drug candidate
for hepatocellular carcinoma (HCC) treatment. However, it is poorly water soluble, limiting its …

Objective: This study aims to detect the enhancement in the oral bioavailability of a poorly
water-soluble antihypertensive drug Olmesartan Medoxomil (OM) due to the formulation of …

Aim: The present study aimed to prepare and evaluate fexofenadine self-microemulsifying
drug-delivery systems (SMEDDS) formulation and to determine and compare its intestinal …

The intestinal lymphatics are considered one of the most specialized pathways, which
promote the absorption of various agents such as vitamins, lipids, xenobiotics, and lipophilic …