The population genetics of pathogenic Escherichia coli
E Denamur, O Clermont, S Bonacorsi… - Nature Reviews …, 2021 - nature.com
Escherichia coli is a commensal of the vertebrate gut that is increasingly involved in various
intestinal and extra-intestinal infections as an opportunistic pathogen. Numerous pathotypes …
intestinal and extra-intestinal infections as an opportunistic pathogen. Numerous pathotypes …
Alternatives to antibiotics—a pipeline portfolio review
L Czaplewski, R Bax, M Clokie, M Dawson… - The Lancet infectious …, 2016 - thelancet.com
Antibiotics have saved countless lives and enabled the development of modern medicine
over the past 70 years. However, it is clear that the success of antibiotics might only have …
over the past 70 years. However, it is clear that the success of antibiotics might only have …
Characterization of antimicrobial-resistant Gram-negative bacteria that cause neonatal sepsis in seven low-and middle-income countries
Antimicrobial resistance in neonatal sepsis is rising, yet mechanisms of resistance that often
spread between species via mobile genetic elements, ultimately limiting treatments in low …
spread between species via mobile genetic elements, ultimately limiting treatments in low …
iML1515, a knowledgebase that computes Escherichia coli traits
Figure 1 iML1515 genome-scale reconstruction.(a) The iML1515 model contains 1,515
open reading frames that encode enzymes that catalyze 2,719 reactions involving 1,192 …
open reading frames that encode enzymes that catalyze 2,719 reactions involving 1,192 …
Systematic longitudinal survey of invasive Escherichia coli in England demonstrates a stable population structure only transiently disturbed by the emergence of …
Escherichia coli associated with urinary tract infections and bacteremia has been intensively
investigated, including recent work focusing on the virulent, globally disseminated, multidrug …
investigated, including recent work focusing on the virulent, globally disseminated, multidrug …
[HTML][HTML] Diarrheagenic Escherichia coli
Most Escherichia coli strains live harmlessly in the intestines and rarely cause disease in
healthy individuals. Nonetheless, a number of pathogenic strains can cause diarrhea or …
healthy individuals. Nonetheless, a number of pathogenic strains can cause diarrhea or …
A low-cost, thermostable, cell-free protein synthesis platform for on-demand production of conjugate vaccines
Cell-free protein synthesis systems that can be lyophilized for long-term, non-refrigerated
storage and transportation have the potential to enable decentralized biomanufacturing …
storage and transportation have the potential to enable decentralized biomanufacturing …
Are Escherichia coli Pathotypes Still Relevant in the Era of Whole-Genome Sequencing?
The empirical and pragmatic nature of diagnostic microbiology has given rise to several
different schemes to subtype E. coli, including biotyping, serotyping, and pathotyping. These …
different schemes to subtype E. coli, including biotyping, serotyping, and pathotyping. These …
[HTML][HTML] Enterotoxigenic Escherichia coli (ETEC) vaccines: Priority activities to enable product development, licensure, and global access
I Khalil, R Walker, CK Porter, F Muhib, R Chilengi… - Vaccine, 2021 - Elsevier
Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes
substantial morbidity and mortality predominantly in paediatric populations in low-and …
substantial morbidity and mortality predominantly in paediatric populations in low-and …
Whole genome sequencing and metagenomics for outbreak investigation, source attribution and risk assessment of food‐borne microorganisms
EFSA Panel on Biological Hazards (EFSA … - EFSA …, 2019 - Wiley Online Library
This Opinion considers the application of whole genome sequencing (WGS) and
metagenomics for outbreak investigation, source attribution and risk assessment of food …
metagenomics for outbreak investigation, source attribution and risk assessment of food …