Opportunities and challenges in targeted therapy and immunotherapy for pancreatic cancer
D Cao, Q Song, J Li, Y Jiang, Z Wang… - Expert reviews in …, 2021 - cambridge.org
Pancreatic cancer is one of the most malignant tumours with a poor prognosis. In recent
years, the incidence of pancreatic cancer is on the rise. Traditional chemotherapy and …
years, the incidence of pancreatic cancer is on the rise. Traditional chemotherapy and …
[HTML][HTML] The heterogeneity of the tumor microenvironment as essential determinant of development, progression and therapy response of pancreatic cancer
Group Young Researchers in Inflammatory … - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is still one of the deadliest
cancers in western countries. It is commonly diagnosed at advanced stages and most anti …
cancers in western countries. It is commonly diagnosed at advanced stages and most anti …
[HTML][HTML] The RNA methyltransferase NSUN6 suppresses pancreatic cancer development by regulating cell proliferation
R Yang, X Liang, H Wang, M Guo, H Shen, Y Shi… - …, 2021 - thelancet.com
Background Pancreatic cancer (PC) is one of the most lethal solid malignancies in the world
due to its excessive cell proliferation and aggressive metastatic features. Emerging …
due to its excessive cell proliferation and aggressive metastatic features. Emerging …
[HTML][HTML] Identification of m6A-related genes and m6A RNA methylation regulators in pancreatic cancer and their association with survival
Y Geng, R Guan, W Hong, B Huang, P Liu… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background N6-methyladenosine (m6A) modification holds an important position in
tumorigenesis and metastasis because it can change gene expression and even function in …
tumorigenesis and metastasis because it can change gene expression and even function in …
[HTML][HTML] Excellent effects and possible mechanisms of action of a new antibody–drug conjugate against EGFR-positive triple-negative breast cancer
DD Zhou, WQ Bai, XT Zhai, LP Sun, YS Zhen… - Military Medical …, 2021 - Springer
Background Triple-negative breast cancer (TNBC) is the most aggressive subtype and
occurs in approximately 15–20% of diagnosed breast cancers. TNBC is characterized by its …
occurs in approximately 15–20% of diagnosed breast cancers. TNBC is characterized by its …
EGFR-targeted and gemcitabine-incorporated chemogene for combinatorial pancreatic cancer treatment
Pancreatic cancer stands out as a recognized intractable tumor due to its high malignancy
and mortality rates, which are largely attributed to the insensitivity of current clinical …
and mortality rates, which are largely attributed to the insensitivity of current clinical …
[HTML][HTML] Unravelling the Triad of Lung Cancer, Drug Resistance, and Metabolic Pathways
Lung cancer, characterized by its heterogeneity, presents a significant challenge in
therapeutic management, primarily due to the development of resistance to conventional …
therapeutic management, primarily due to the development of resistance to conventional …
Targeted Fluorescence Imaging and Anti-Tumor Effects of QDs-NGR Nanoparticles on Pancreatic Cancer Cells
G Tan, B Li, YJ Zhang, RY Zhang… - Science of Advanced …, 2021 - ingentaconnect.com
With a poor prognosis and lack of effective therapies, pancreatic cancer is one of the most
deadly tumors. The early diagnosis of pancreatic cancer is particularly important to improve …
deadly tumors. The early diagnosis of pancreatic cancer is particularly important to improve …
Therapeutic targeting of glutamine metabolism in colorectal cancer
Colorectal cancer is one of the most commonly diagnosed incurable multifactorial
malignancies in the world. To date, there are no promising noninvasive therapeutic tools that …
malignancies in the world. To date, there are no promising noninvasive therapeutic tools that …
[PDF][PDF] Molecular underpinnings of circadian mechanism, chronotherapy and lung cancer: a mini-review
JP Choudhary, T Sahu, B Pande - Polymorphism, 2022 - researchgate.net
Humans adjust to the diurnally varying light-dark cycle in nature through circadian rhythm, a
phenomenon of about 24 hour oscillations in biological processes. The circadian rhythm …
phenomenon of about 24 hour oscillations in biological processes. The circadian rhythm …