A little over one hundred years ago, a vanadium-containing compound was assessed
clinically for use in treatment of human diabetic patients. The results were somewhat …

In biological systems metal ions promote responses that range from deficiency to toxicity.
Some, such as iron and zinc, have a known optimal intake range for normal, healthy …

The field of medicinal inorganic chemistry has evolved with three conceptual aims: the
introduction of metal ions to the biological system, manipulation and redistribution of metal …

This tutorial review will highlight recent advances in medicinal inorganic chemistry
pertaining to the use of multifunctional ligands for enhanced effect. Ligands that adequately …

An overview is presented of selected metal-based pharmaceuticals, either diagnostic or
therapeutic, with emphasis on specific attributes and in vivo interactions of these compounds …

Novel bis [4-hydroxy-3-methoxyphenyl]-1, 6-heptadiene-3, 5-dione (curcumin) complexes
with the formula, ML3, where M is Ga (III) or In (III), or of the formula, ML2 where M is [VO] 2+ …

Thiazolidinedione is an important heterocyclic ring system, a pharmacophore and a
privileged scaffold in medicinal chemistry; is a derivative of thiazolidine ring which came into …

Diabetes or diabetes mellitus is a complex or polygenic disorder, which is characterized by
increased levels of glucose (hyperglycemia) and deficiency in insulin secretion or resistance …

The current status and likely future directions of complexes of V (V/IV), Cr (III), Mo (VI), W (VI),
Zn (II), Cu (II), and Mn (III) as potential oral drugs against type 2 diabetes are reviewed. We …

Vanadium causes a variety of toxic effects such as hematological and biochemical changes,
eg, hemolysis and decrease in erythrocyte count/hemoglobin level/hematocrit index …