Aim To evaluate studies on the psychometric properties of measurement tools used to
quantify functional mobility in children with hereditary spastic paraplegia (HSP) and other …

Background Hereditary spastic paraplegias (HSPs) are a group of inheritance diseases
resulting in gait abnormalities, which may be detected using instrumented gait analysis. The …

Objective We study the effectiveness and safety of intrathecal baclofen therapy for the
treatment of spasticity and gait improvement in patients suffering from hereditary spastic …

The predominant clinical feature of patients with Hereditary Spastic Paraparesis (HSP) is
gait disturbance owing to spasticity and weakness of the lower limbs; the spasticity in early …

Background Hereditary spastic paraparesis (HSP) is a group of neurological disorders
characterised by slowly progressive increasing muscle tone, predominantly in the lower …

Recently, nabiximols was approved as a treatment in MS spasticity. Data leading to approval
and clinical use of nabiximols, although widely recognised, are based on subjective scales …

Intrathecal baclofen (ITB) therapy effectively treats spasticity caused by brain or spinal cord
lesions. However, only a few studies compare the course of treatment for different diseases …

Introduction: Treatment with intrathecal baclofen (ITB) is a therapeutic option in the
management of severe spasticity in patients with hereditary spastic paraparesis (HSP) …

Objective A comprehensive treatment of Hereditary Spastic Paraplegia (HSP) should
consider the specific pathophysiological changes in the spinal cord. Here we reported a …

Patients with hereditary spastic paraplegia (HSP) often resemble patients with mild spastic
diplegia (SD), although their motor limitations differ. The aim of this study was to analyse …