The serotonin transporter (SERT) terminates serotonin signaling by using sodium and
chloride gradients to drive reuptake of serotonin into presynaptic neurons and is the target of …

Found in all domains of life, transporters belonging to the LeuT-fold class mediate the import
and exchange of hydrophilic and charged compounds such as amino acids, metals, and …

NMDA-type glutamate receptors (NMDARs) constitute one of the main glutamate (Glu)
targets in the central nervous system and are involved in synaptic plasticity, which is the …

Depression is a common mental disorder. The standard medical treatment is the selective
serotonin reuptake inhibitors (SSRIs). All characterized SSRIs are competitive inhibitors of …

Noradrenaline, also known as norepinephrine, has a wide range of activities and effects on
most brain cell types. Its reuptake from the synaptic cleft heavily relies on the noradrenaline …

The serotonin transporter (SERT), a member of the neurotransmitter: sodium symporter
family, is responsible for termination of serotonergic signaling by re-uptake of serotonin (5 …

The concentrative power of the transporters for dopamine (DAT), norepinephrine (NET), and
serotonin (SERT) is thought to be fueled by the transmembrane Na+ gradient, but it is …

Transporting small molecules across cell membranes is an essential process in cell
physiology. Many structurally diverse, secondary active transporters harness …

The dopamine transporter (DAT) belongs to the neurotransmitter/sodium symporter (NSS)
family of membrane proteins that are responsible for reuptake of neurotransmitters from the …

The dopamine transporter is a member of the neurotransmitter: sodium symporters (NSSs),
which are responsible for termination of neurotransmission through Na+-driven reuptake of …