A major roadblock to achieving a cure for human immunodeficiency virus type one (HIV-1) is
the persistence of latent viral infections in the cells and tissue compartments of an infected …

HIV-1 replication in the gastrointestinal (GI) tract causes severe CD4+ T-cell depletion and
disruption of the protective epithelial barrier in the intestinal mucosa, causing microbial …

Latently-infected CD4+ T cells are widely considered to be the major barrier to a cure for
HIV. Much of our understanding of HIV latency comes from latency models and blood cells …

For decades, studies of natural killer (NK) cells have focused on those found in peripheral
blood (PBNK cells) as the prototype for NK cell biology. Only recently have researchers …

The final obstacle to achieving a cure to HIV/AIDS is the presence of latent HIV reservoirs
scattered throughout the body. Although antiretroviral therapy maintains plasma viral loads …

Simple Summary Over 70% of the liver comprises of parenchymal cells (named
hepatocytes) and the rest 30% of cells are the non-parenchymal cells, which include …

Human immunodeficiency virus (HIV) 1 infection is known to cause gut microbiota dysbiosis.
Among the causes is the direct infection of HIV-1 in gut-resident CD4+ T cells, causing a …

Studies assessing the gut mucosal immune balance in HIV-infected patients using intestinal
samples are scarce. In this study, we used intestinal mucosal specimens from the ileocecal …

Background and Aims Human immunodeficiency virus (HIV) infection is associated with
several immune-mediated disorders. However, the risk of inflammatory bowel disease (IBD) …

The cure for chronic human immunodeficiency virus (HIV) infections has been a goal
pursued since the antiretroviral therapy that improved the clinical conditions of patients …