Here we present a guide to ion mobility mass spectrometry experiments, which covers both
linear and nonlinear methods: what is measured, how the measurements are done, and how …

Highlights•CCS distributions and shifts contain valuable information about
analytes.•Compound-dependent effects of gas, field and temperature explain calibration …

Trapped ion mobility spectrometry (TIMS) hybridized with mass spectrometry (MS) is a
relatively recent advance in the field of ion mobility mass spectrometry (IMMS). The basic …

Recent advances in efficiency and ease of implementation have rekindled interest in ion
mobility spectrometry, a technique that separates gas phase ions by their size and shape …

Native mass spectrometry (nMS) is evolving into a workhorse for structural biology. The
plethora of online and offline preparation, separation, and purification methods as well as …

Native mass spectrometry (MS) is aimed at preserving and determining the native structure,
composition, and stoichiometry of biomolecules and their complexes from solution after they …

Ion mobility-mass spectrometry (IM-MS) can be a powerful tool for determining structural
information about ions in the gas phase, from small covalent analytes to large, native-like or …

Highlights•Advantages/limitations of IMMS for metabolomics are reviewed.•IMMS can offer
improved compound identification and metabolome coverage.•Commercial IMMS systems …

With recent advances in ionization sources and instrumentation, ion mobility spectrometers
(IMS) have transformed from a detector for chemical warfare agents and explosives to a …

Antibody-drug conjugates (ADCs) are one of the fastest growing classes of anticancer
therapies. Combining the high targeting specificity of monoclonal antibodies (mAbs) with …