Unraveling the crosstalk between melanoma and immune cells in the tumor microenvironment

M Marzagalli, ND Ebelt, ER Manuel - Seminars in cancer biology, 2019 - Elsevier
Cutaneous melanoma is the most common skin cancer with an incidence that has been
rapidly increasing in the past decades. Melanomas are among the most immunogenic …

The widespread regulation of microRNA biogenesis, function and decay

J Krol, I Loedige, W Filipowicz - Nature reviews genetics, 2010 - nature.com
MicroRNAs (miRNAs) are a large family of post-transcriptional regulators of gene expression
that are∼ 21 nucleotides in length and control many developmental and cellular processes …

DNA methylation and cancer

M Kulis, M Esteller - Advances in genetics, 2010 - Elsevier
DNA methylation is one of the most intensely studied epigenetic modifications in mammals.
In normal cells, it assures the proper regulation of gene expression and stable gene …

[HTML][HTML] microRNAs derived from circulating exosomes as noninvasive biomarkers for screening and diagnosing lung cancer

R Cazzoli, F Buttitta, M Di Nicola, S Malatesta… - Journal of thoracic …, 2013 - Elsevier
Introduction: Lung cancer is the highest cause of mortality among tumor pathologies
worldwide. There are no validated techniques for an early detection of pulmonary cancer …

CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17

K Han, FW Wang, CH Cao, H Ling, JW Chen, RX Chen… - Molecular cancer, 2020 - Springer
Background Metastasis causes the vast majority of colorectal carcinoma (CRC)-related
deaths. However, little is known about the specific traits and underlying mechanisms of …

Cancer epigenetics

R Taby, JPJ Issa - CA: a cancer journal for clinicians, 2010 - Wiley Online Library
Epigenetics refers to stable alterations in gene expression with no underlying modifications
in the genetic sequence and is best exemplified by differentiation, in which multiple cell …

Mechanisms of chemical carcinogenicity and mutagenicity: a review with implications for predictive toxicology

R Benigni, C Bossa - Chemical reviews, 2011 - ACS Publications
Mechanisms of Chemical Carcinogenicity and Mutagenicity: A Review with Implications for
Predictive Toxicology | Chemical Reviews ACS ACS Publications C&EN CAS Find my …

[HTML][HTML] Dysregulation of microRNAs in cancer: playing with fire

SA Melo, M Esteller - FEBS letters, 2011 - Elsevier
MicroRNAs [1] have emerged as key post-transcriptional regulators of gene expression,
involved in various physiological and pathological processes. It was found that several …

[HTML][HTML] Plasma microRNAs as novel biomarkers for early detection of lung cancer

D Zheng, S Haddadin, Y Wang, LQ Gu… - … journal of clinical and …, 2011 - ncbi.nlm.nih.gov
A diagnosis of lung cancer at its early stages is vital for improving the survival rate of
patients. MicroRNAs (miRNAs), a family of 19-to 25-nucleotide non-coding small RNAs, are …

Epigenetic impact of dietary polyphenols in cancer chemoprevention: lifelong remodeling of our epigenomes

WV Berghe - Pharmacological research, 2012 - Elsevier
Cancer, as one of the non-communicable diseases, remains one of the leading causes of
death around the world. Recently, epigenetic changes in DNA methylation patterns at CpG …