Particle design via spherical agglomeration is a size enlargement technique used in various
bulk and fine chemical industries, with recent interest extending into pharmaceuticals, in …

The morphological characterization of aggregates or agglomerates using image analysis is
an increasingly active area of research, whether in the chemical, environmental or civil …

Of utmost importance in the crystallization of active pharmaceutical ingredients (APIs) in the
pharmaceutical industry is to produce crystals of good physical, processing, and …

Batch granulation experiments on a lab-scale drum granulator for a Calcite/Polyvinyl alcohol
in water (Calcite/PVOH–H2O) system are presented in this study. Experimental studies were …

This paper presents an experimental technique for tuning the size of spherical agglomerates
together with a simple model that provides qualitative information on the agglomerate size …

Spherical crystallization is a particle size enlargement technique that can provide significant
process and micromeritic benefits to the production of active pharmaceutical ingredients. To …

The population balance model is the common approach to simulation and prediction of the
size distribution and other properties of particulate systems. Population balance models …

Spherical agglomerates of benzoic acid have been successfully prepared by semi-batch,
agitated vessel, drowning-out crystallization in water–ethanol–toluene mixtures. Benzoic …

Understanding the evolution of liquid–liquid dispersion is a key factor in operation and
control of emulsification process. A dynamic tracking of an evolving droplet size distribution …

Spherical agglomeration is a well-known process intensification method that offers several
advantages, including material and energy savings associated with the reduction of …