Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors

L Galluzzi, J Humeau, A Buqué, L Zitvogel… - Nature reviews Clinical …, 2020 - nature.com
Conventional chemotherapeutics have been developed into clinically useful agents based
on their ability to preferentially kill malignant cells, generally owing to their elevated …

Cold atmospheric plasma delivery for biomedical applications

Z Chen, G Chen, R Obenchain, R Zhang, F Bai, T Fang… - Materials Today, 2022 - Elsevier
As the fourth state of matter, plasma's unique properties and interactions with other states of
matter offer many promising opportunities for investigation and discovery. In particular, cold …

Low-temperature plasma for biology, hygiene, and medicine: Perspective and roadmap

M Laroussi, S Bekeschus, M Keidar… - … on Radiation and …, 2021 - ieeexplore.ieee.org
Plasma, the fourth and most pervasive state of matter in the visible universe, is a fascinating
medium that is connected to the beginning of our universe itself. Man-made plasmas are at …

Molecular mechanisms of the efficacy of cold atmospheric pressure plasma (CAP) in cancer treatment

ML Semmler, S Bekeschus, M Schäfer, T Bernhardt… - Cancers, 2020 - mdpi.com
Recently, the potential use of cold atmospheric pressure plasma (CAP) in cancer treatment
has gained increasing interest. Especially the enhanced selective killing of tumor cells …

Plasma-treated solutions (PTS) in cancer therapy

H Tanaka, S Bekeschus, D Yan, M Hori, M Keidar… - Cancers, 2021 - mdpi.com
Simple Summary Cold physical plasma is a partially ionized gas generating various reactive
oxygen and nitrogen species (ROS/RNS) simultaneously. ROS/RNS have therapeutic …

[HTML][HTML] Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell …

LF Boullosa, J Van Loenhout, T Flieswasser… - Redox biology, 2021 - Elsevier
Auranofin (AF) is an FDA-approved antirheumatic drug with anticancer properties that acts
as a thioredoxin reductase 1 (TrxR) inhibitor. The exact mechanisms through which AF …

Immunogenic cell death: an emerging target in gastrointestinal cancers

M Chiaravalli, A Spring, A Agostini, G Piro, C Carbone… - Cells, 2022 - mdpi.com
Immunogenic cell death (ICD) is a regulated form of cell death that induces the activation of
both innate and adaptive immune responses through the release of damage-associated …

Current state of cold atmospheric plasma and cancer‐immunity cycle: therapeutic relevance and overcoming clinical limitations using hydrogels

M Živanić, A Espona‐Noguera, A Lin… - Advanced …, 2023 - Wiley Online Library
Cold atmospheric plasma (CAP) is a partially ionized gas that gains attention as a well‐
tolerated cancer treatment that can enhance anti‐tumor immune responses, which are …

Auranofin and cold atmospheric plasma synergize to trigger distinct cell death mechanisms and immunogenic responses in glioblastoma

J Van Loenhout, L Freire Boullosa, D Quatannens… - Cells, 2021 - mdpi.com
Targeting the redox balance of malignant cells via the delivery of high oxidative stress
unlocks a potential therapeutic strategy against glioblastoma (GBM). We investigated a …

Cold physical plasma in cancer therapy: mechanisms, signaling, and immunity

F Faramarzi, P Zafari, M Alimohammadi… - Oxidative medicine …, 2021 - Wiley Online Library
Despite recent advances in therapy, cancer still is a devastating and life‐threatening
disease, motivating novel research lines in oncology. Cold physical plasma, a partially …