Mitochondrial metabolism and dynamics in pancreatic beta cell glucose sensing

GA Rutter, V Sidarala, BA Kaufman… - Biochemical …, 2023 - portlandpress.com
Glucose-regulated insulin secretion becomes defective in all forms of diabetes. The
signaling mechanisms through which the sugar acts on the ensemble of beta cells within the …

A role and mechanism for redox sensing by SENP1 in β-cell responses to high fat feeding

H Lin, K Suzuki, N Smith, X Li, L Nalbach… - Nature …, 2024 - nature.com
Pancreatic β-cells respond to metabolic stress by upregulating insulin secretion, however
the underlying mechanisms remain unclear. Here we show, in β-cells from overweight …

[图书][B] The impact of novel AMP-activated protein kinase (AMPK) activators and glucose variability on pancreatic α-cell function

K Partridge - 2023 - search.proquest.com
The physiological maintenance of normal blood glucose levels (euglycaemia) and
prevention of hypoglycaemia is controlled by the intricate process of hormone release from …