Recent developments in bioprocessing of recombinant proteins: expression hosts and process development

NK Tripathi, A Shrivastava - Frontiers in Bioengineering and …, 2019 - frontiersin.org
Infectious diseases, along with cancers, are among the main causes of death among
humans worldwide. The production of therapeutic proteins for treating diseases at large …

Current perspective on production and applications of microbial cellulases: a review

N Bhardwaj, B Kumar, K Agrawal, P Verma - Bioresources and …, 2021 - Springer
The potential of cellulolytic enzymes has been widely studied and explored for
bioconversion processes and plays a key role in various industrial applications. Cellulase, a …

Cellulases and beyond: the first 70 years of the enzyme producer Trichoderma reesei

RH Bischof, J Ramoni, B Seiboth - Microbial cell factories, 2016 - Springer
More than 70 years ago, the filamentous ascomycete Trichoderma reesei was isolated on
the Solomon Islands due to its ability to degrade and thrive on cellulose containing fabrics …

Revisiting cellulase production and redefining current strategies based on major challenges

RC Kuhad, D Deswal, S Sharma… - … and Sustainable Energy …, 2016 - Elsevier
Lignocellulosic biomass has been considered as an important and sustainable source of
renewable energy. Cellulose constitutes the major component of the lignocellulosic biomass …

Exploring industrial and natural Saccharomyces cerevisiae strains for the bio-based economy from biomass: the case of bioethanol

L Favaro, T Jansen, WH van Zyl - Critical reviews in biotechnology, 2019 - Taylor & Francis
Saccharomyces cerevisiae is the preferred microorganism for the production of bioethanol
from biomass. Industrial strain development for first-generation ethanol from sugar cane and …

Challenges and advances in the heterologous expression of cellulolytic enzymes: a review

C Lambertz, M Garvey, J Klinger, D Heesel… - Biotechnology for …, 2014 - Springer
Second generation biofuel development is increasingly reliant on the recombinant
expression of cellulases. Designing or identifying successful expression systems is thus of …

Microbial lignin peroxidases: applications, production challenges and future perspectives

ODV Biko, M Viljoen-Bloom, WH van Zyl - Enzyme and Microbial …, 2020 - Elsevier
Lignin serves as the most abundant source of aromatic high-value products, but it has
remained underexploited due to its inert and recalcitrant nature. White-rot basidiomycetes …

Progress and challenges in the engineering of non-cellulolytic microorganisms for consolidated bioprocessing

R den Haan, E van Rensburg, SH Rose… - Current opinion in …, 2015 - Elsevier
Highlights•Consolidated bioprocessing is a promising technology to enable cellulose
utilization.•Yeast, filamentous fungi and bacteria have been engineered as CBP organisms.• …

Heterologous production of cellulose-and starch-degrading hydrolases to expand Saccharomyces cerevisiae substrate utilization: lessons learnt

R den Haan, SH Rose, RA Cripwell, KM Trollope… - Biotechnology …, 2021 - Elsevier
Selected strains of Saccharomyces cerevisiae are used for commercial bioethanol
production from cellulose and starch, but the high cost of exogenous enzymes for substrate …

Molecular biology interventions for activity improvement and production of industrial enzymes

SK Bhatia, N Vivek, V Kumar, N Chandel, M Thakur… - Bioresource …, 2021 - Elsevier
Metagenomics and directed evolution technology have brought a revolution in search of
novel enzymes from extreme environment and improvement of existing enzymes and tuning …